ENSG00000181698


Homo sapiens

Features
Gene ID: ENSG00000181698
  
Biological name :OR5T1
  
Synonyms : olfactory receptor family 5 subfamily T member 1 / OR5T1 / Q8NG75
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 11
Strand: 1
Band: q12.1
Gene start: 56274154
Gene end: 56276819
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000493364
Ensembl peptide - ENSP00000493084
NCBI entrez gene - 390155     See in Manteia.
RefSeq - NM_001004745
RefSeq Peptide - NP_001004745
swissprot - Q8NG75
swissprot - A0A126GVL6
Ensembl - ENSG00000181698
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Olfr1093ENSMUSG00000047969Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
OR5T3 / Q8NGG3 / olfactory receptor family 5 subfamily T member 3ENSG0000017248980
OR5T2 / Q8NGG2 / olfactory receptor family 5 subfamily T member 2ENSG0000018171874
OR5W2 / Q8NH69 / olfactory receptor family 5 subfamily W member 2ENSG0000018761252
OR5AR1 / Q8NGP9 / olfactory receptor family 5 subfamily AR member 1 (gene/pseudogene)ENSG0000017245950
OR5AS1 / Q8N127 / olfactory receptor family 5 subfamily AS member 1ENSG0000018178549
OR5C1 / Q8NGR4 / olfactory receptor family 5 subfamily C member 1ENSG0000014821548


Protein motifs (from Interpro)
Interpro ID Name
 IPR000276  G protein-coupled receptor, rhodopsin-like
 IPR000725  Olfactory receptor
 IPR017452  GPCR, rhodopsin-like, 7TM


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001963 synaptic transmission, dopaminergic IBA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007194 negative regulation of adenylate cyclase activity IBA
 biological_processGO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway IBA
 biological_processGO:0007608 sensory perception of smell IEA
 biological_processGO:0009636 response to toxic substance IBA
 biological_processGO:0014059 regulation of dopamine secretion IBA
 biological_processGO:0042493 response to drug IBA
 biological_processGO:0043266 regulation of potassium ion transport IBA
 biological_processGO:0048148 behavioral response to cocaine IBA
 biological_processGO:0048149 behavioral response to ethanol IBA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0050911 detection of chemical stimulus involved in sensory perception of smell IEA
 biological_processGO:0051481 negative regulation of cytosolic calcium ion concentration IBA
 biological_processGO:0051967 negative regulation of synaptic transmission, glutamatergic IBA
 biological_processGO:0060158 phospholipase C-activating dopamine receptor signaling pathway IBA
 biological_processGO:1901386 negative regulation of voltage-gated calcium channel activity IBA
 cellular_componentGO:0005886 plasma membrane TAS
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030672 synaptic vesicle membrane IBA
 molecular_functionGO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go IBA
 molecular_functionGO:0004871 obsolete signal transducer activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity IEA
 molecular_functionGO:0004984 olfactory receptor activity IEA
 molecular_functionGO:0035240 dopamine binding IBA


Pathways (from Reactome)
Pathway description
Olfactory Signaling Pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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