ENSG00000182628


Homo sapiens

Features
Gene ID: ENSG00000182628
  
Biological name :SKA2
  
Synonyms : Q8WVK7 / SKA2 / spindle and kinetochore associated complex subunit 2
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: -1
Band: q22
Gene start: 59109951
Gene end: 59155269
  
Corresponding Affymetrix probe sets: 225684_at (Human Genome U133 Plus 2.0 Array)   225686_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000464558
Ensembl peptide - ENSP00000463167
Ensembl peptide - ENSP00000463315
Ensembl peptide - ENSP00000333433
Ensembl peptide - ENSP00000411231
Ensembl peptide - ENSP00000462197
Ensembl peptide - ENSP00000462220
Ensembl peptide - ENSP00000462574
Ensembl peptide - ENSP00000462918
NCBI entrez gene - 348235     See in Manteia.
OMIM - 616674
RefSeq - XM_011524745
RefSeq - NM_001100595
RefSeq - NM_001330399
RefSeq - NM_182620
RefSeq Peptide - NP_872426
RefSeq Peptide - NP_001094065
RefSeq Peptide - NP_001317328
swissprot - Q8WVK7
swissprot - J3KRW9
swissprot - J3KRZ0
swissprot - J3KSP0
swissprot - J3QKN8
swissprot - J3KTC5
swissprot - J3QL03
swissprot - J3QS74
Ensembl - ENSG00000182628
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ska2ENSDARG00000114038Danio rerio
 SKA2ENSGALG00000005090Gallus gallus
 Ska2ENSMUSG00000020492Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026762  Spindle and kinetochore-associated protein 2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000278 mitotic cell cycle IMP
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007059 chromosome segregation IEA
 biological_processGO:0007062 sister chromatid cohesion TAS
 biological_processGO:0031110 regulation of microtubule polymerization or depolymerization IDA
 biological_processGO:0051301 cell division IEA
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0000776 kinetochore IEA
 cellular_componentGO:0000777 condensed chromosome kinetochore IEA
 cellular_componentGO:0000940 condensed chromosome outer kinetochore IEA
 cellular_componentGO:0005694 chromosome IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0005876 spindle microtubule IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IEA


Pathways (from Reactome)
Pathway description
Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal
Separation of Sister Chromatids
Resolution of Sister Chromatid Cohesion
RHO GTPases Activate Formins
Mitotic Prometaphase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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