ENSG00000184719


Homo sapiens

Features
Gene ID: ENSG00000184719
  
Biological name :RNLS
  
Synonyms : Q5VYX0 / renalase, FAD dependent amine oxidase / RNLS
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 10
Strand: -1
Band: q23.31
Gene start: 88273864
Gene end: 88584530
  
Corresponding Affymetrix probe sets: 220564_at (Human Genome U133 Plus 2.0 Array)   223824_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000332530
Ensembl peptide - ENSP00000361015
Ensembl peptide - ENSP00000387577
NCBI entrez gene - 55328     See in Manteia.
OMIM - 609360
RefSeq - XM_017016383
RefSeq - NM_001031709
RefSeq - NM_018363
RefSeq - XM_011539927
RefSeq - XM_017016380
RefSeq - XM_017016381
RefSeq - XM_017016382
RefSeq - XM_005269946
RefSeq - XM_005269947
RefSeq - XM_005269948
RefSeq - XM_005269949
RefSeq - XM_005269950
RefSeq - XM_011539924
RefSeq Peptide - NP_001026879
RefSeq Peptide - NP_060833
swissprot - Q5VYX0
swissprot - F6XA08
Ensembl - ENSG00000184719
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rnlsENSDARG00000012453Danio rerio
 RNLSENSGALG00000029829Gallus gallus
 RnlsENSMUSG00000071573Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR002937  Amine oxidase
 IPR036188  FAD/NAD(P)-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002931 response to ischemia IEA
 biological_processGO:0010459 negative regulation of heart rate IDA
 biological_processGO:0034356 NAD biosynthesis via nicotinamide riboside salvage pathway TAS
 biological_processGO:0045776 negative regulation of blood pressure IDA
 biological_processGO:0055114 oxidation-reduction process IEA
 biological_processGO:0071869 response to catecholamine IEA
 biological_processGO:0071871 response to epinephrine IEA
 biological_processGO:1902074 response to salt IEA
 cellular_componentGO:0005576 extracellular region TAS
 cellular_componentGO:0005615 extracellular space IEA
 molecular_functionGO:0016491 oxidoreductase activity IEA
 molecular_functionGO:0016651 oxidoreductase activity, acting on NAD(P)H TAS
 molecular_functionGO:0051379 epinephrine binding IDA
 molecular_functionGO:0070404 NADH binding IDA
 molecular_functionGO:0097621 monoamine oxidase activity IMP


Pathways (from Reactome)
Pathway description
Nicotinamide salvaging


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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