ENSG00000186088


Homo sapiens

Features
Gene ID: ENSG00000186088
  
Biological name :GSAP
  
Synonyms : A4D1B5 / gamma-secretase activating protein / GSAP
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q11.23
Gene start: 77310751
Gene end: 77416400
  
Corresponding Affymetrix probe sets: 213142_x_at (Human Genome U133 Plus 2.0 Array)   222150_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000396230
Ensembl peptide - ENSP00000415402
Ensembl peptide - ENSP00000402748
Ensembl peptide - ENSP00000257626
NCBI entrez gene - 54103     See in Manteia.
OMIM - 613552
RefSeq - XM_017012351
RefSeq - XM_017012344
RefSeq - XM_017012345
RefSeq - XM_017012346
RefSeq - XM_017012347
RefSeq - XM_017012348
RefSeq - XM_017012349
RefSeq - XM_017012350
RefSeq - NM_001350898
RefSeq - NM_001350900
RefSeq - NM_017439
RefSeq - XM_011516325
RefSeq - XM_011516326
RefSeq - XM_011516327
RefSeq - XM_011516330
RefSeq - XM_017012343
RefSeq Peptide - NP_001337829
RefSeq Peptide - NP_059135
RefSeq Peptide - NP_001337827
swissprot - C9JRG7
swissprot - A4D1B5
swissprot - B7ZL33
swissprot - H7C0Q7
Ensembl - ENSG00000186088
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gsapENSDARG00000045481Danio rerio
 GSAPENSGALG00000008312Gallus gallus
 GsapENSMUSG00000039934Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026172  Gamma-secretase-activating protein family
 IPR028010  Gamma-secretase-activating protein, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030162 regulation of proteolysis IDA
 biological_processGO:1902004 positive regulation of amyloid-beta formation IDA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 molecular_functionGO:0001540 amyloid-beta binding IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr