ENSG00000186591


Homo sapiens

Features
Gene ID: ENSG00000186591
  
Biological name :UBE2H
  
Synonyms : P62256 / UBE2H / ubiquitin conjugating enzyme E2 H
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q32.2
Gene start: 129830732
Gene end: 129952949
  
Corresponding Affymetrix probe sets: 217799_x_at (Human Genome U133 Plus 2.0 Array)   221962_s_at (Human Genome U133 Plus 2.0 Array)   222419_x_at (Human Genome U133 Plus 2.0 Array)   222420_s_at (Human Genome U133 Plus 2.0 Array)   222421_at (Human Genome U133 Plus 2.0 Array)   226637_at (Human Genome U133 Plus 2.0 Array)   226681_at (Human Genome U133 Plus 2.0 Array)   227950_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000419689
Ensembl peptide - ENSP00000347836
Ensembl peptide - ENSP00000419750
Ensembl peptide - ENSP00000417681
Ensembl peptide - ENSP00000419097
Ensembl peptide - ENSP00000417709
NCBI entrez gene - 7328     See in Manteia.
OMIM - 601082
RefSeq - NM_003344
RefSeq - NM_182697
RefSeq - NM_001202498
RefSeq Peptide - NP_001189427
RefSeq Peptide - NP_003335
RefSeq Peptide - NP_874356
swissprot - P62256
swissprot - C9JZG9
swissprot - C9J8Q9
swissprot - A4D1L5
swissprot - H7C4M9
swissprot - C9JZY6
Ensembl - ENSG00000186591
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ube2hENSDARG00000000019Danio rerio
 UBE2HENSGALG00000031975Gallus gallus
 Ube2hENSMUSG00000039159Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000608  Ubiquitin-conjugating enzyme E2
 IPR016135  Ubiquitin-conjugating enzyme/RWD-like
 IPR023313  Ubiquitin-conjugating enzyme, active site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process TAS
 biological_processGO:0016567 protein ubiquitination TAS
 biological_processGO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process IEA
 biological_processGO:0070936 protein K48-linked ubiquitination IDA
 biological_processGO:0070979 protein K11-linked ubiquitination IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004842 ubiquitin-protein transferase activity TAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IBA
 molecular_functionGO:0061630 ubiquitin protein ligase activity IBA
 molecular_functionGO:0061631 ubiquitin conjugating enzyme activity IEA


Pathways (from Reactome)
Pathway description
Synthesis of active ubiquitin: roles of E1 and E2 enzymes
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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