ENSG00000186654


Homo sapiens

Features
Gene ID: ENSG00000186654
  
Biological name :PRR5
  
Synonyms : P85299 / proline rich 5 / PRR5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q13.31
Gene start: 44668547
Gene end: 44737681
  
Corresponding Affymetrix probe sets: 219168_s_at (Human Genome U133 Plus 2.0 Array)   47069_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000392026
Ensembl peptide - ENSP00000485597
Ensembl peptide - ENSP00000480357
Ensembl peptide - ENSP00000479623
Ensembl peptide - ENSP00000410215
Ensembl peptide - ENSP00000407637
Ensembl peptide - ENSP00000400925
Ensembl peptide - ENSP00000006251
Ensembl peptide - ENSP00000337464
Ensembl peptide - ENSP00000384746
Ensembl peptide - ENSP00000384848
NCBI entrez gene - 55615     See in Manteia.
OMIM - 609406
RefSeq - NM_181333
RefSeq - NM_001017528
RefSeq - NM_001017529
RefSeq - NM_001017530
RefSeq - NM_001198721
RefSeq - NM_015366
RefSeq Peptide - NP_001017528
RefSeq Peptide - NP_001017529
RefSeq Peptide - NP_001017530
RefSeq Peptide - NP_001185650
RefSeq Peptide - NP_056181
RefSeq Peptide - NP_851850
swissprot - P85299
swissprot - B1AHG4
swissprot - B1AHG3
swissprot - A8K699
swissprot - A0A024R4U5
swissprot - F8WEZ7
swissprot - G3V0G2
swissprot - E9PH80
Ensembl - ENSG00000186654
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 prr5aENSDARG00000075977Danio rerio
 PRR5ENSGALG00000014213Gallus gallus
 Prr5ENSMUSG00000036106Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PRR5L / Q6MZQ0 / proline rich 5 likeENSG0000013536234


Protein motifs (from Interpro)
Interpro ID Name
 IPR013745  TORC2 component Bit61/PRR5
 IPR016159  Cullin repeat-like-containing domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0032148 activation of protein kinase B activity TAS
 biological_processGO:0038203 TORC2 signaling IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0031932 TORC2 complex IDA


Pathways (from Reactome)
Pathway description
PIP3 activates AKT signaling
CD28 dependent PI3K/Akt signaling
VEGFR2 mediated vascular permeability
Constitutive Signaling by AKT1 E17K in Cancer
Regulation of TP53 Degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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