ENSG00000186919


Homo sapiens

Features
Gene ID: ENSG00000186919
  
Biological name :ZACN
  
Synonyms : Q401N2 / ZACN / zinc activated ion channel
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 17
Strand: 1
Band: q25.1
Gene start: 76071961
Gene end: 76083666
  
Corresponding Affymetrix probe sets: 1555550_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000391936
Ensembl peptide - ENSP00000397489
Ensembl peptide - ENSP00000334854
NCBI entrez gene - 353174     See in Manteia.
OMIM - 610935
RefSeq - NM_180990
RefSeq Peptide - NP_851321
swissprot - Q401N2
Ensembl - ENSG00000186919
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CR759836.1ENSDARG00000115573Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR006201  Neurotransmitter-gated ion-channel
 IPR006202  Neurotransmitter-gated ion-channel ligand-binding domain
 IPR018000  Neurotransmitter-gated ion-channel, conserved site
 IPR036719  Neurotransmitter-gated ion-channel transmembrane domain superfamily
 IPR036734  Neurotransmitter-gated ion-channel ligand-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0010043 response to zinc ion IDA
 biological_processGO:0034220 ion transmembrane transport IDA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005230 extracellular ligand-gated ion channel activity IEA
 molecular_functionGO:0008270 zinc ion binding IC
 molecular_functionGO:0015276 ligand-gated ion channel activity IDA
 molecular_functionGO:0022850 serotonin-gated cation-selective channel activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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