ENSG00000196433


Homo sapiens

Features
Gene ID: ENSG00000196433
  
Biological name :ASMT
  
Synonyms : acetylserotonin O-methyltransferase / ASMT / P46597
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: X
Strand: 1
Band: p22.33
Gene start: 1615001
Gene end: 1643081
  
Corresponding Affymetrix probe sets: 206779_s_at (Human Genome U133 Plus 2.0 Array)   210551_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000370631
Ensembl peptide - ENSP00000370639
Ensembl peptide - ENSP00000392053
Ensembl peptide - ENSP00000370627
NCBI entrez gene - 438     See in Manteia.
OMIM - 300015
OMIM - 402500
RefSeq - NM_001171038
RefSeq - NM_001171039
RefSeq - NM_004043
RefSeq Peptide - NP_001164509
RefSeq Peptide - NP_001164510
RefSeq Peptide - NP_004034
swissprot - I7HFW6
swissprot - X5D2A4
swissprot - A0A024RBT9
swissprot - X5D784
swissprot - P46597
Ensembl - ENSG00000196433
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 asmtENSDARG00000098249Danio rerio
 ASMTENSGALG00000016685Gallus gallus
 AsmtENSMUSG00000093806Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ASMTL / O95671 / acetylserotonin O-methyltransferase likeENSG0000016909339


Protein motifs (from Interpro)
Interpro ID Name
 IPR001077  O-methyltransferase, family 2
 IPR016461  O-methyltransferase COMT-type
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase
 IPR031725  Acetylserotonin O-methyltransferase, dimerisation domain
 IPR036388  Winged helix-like DNA-binding domain superfamily
 IPR036390  Winged helix DNA-binding domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006412 translation TAS
 biological_processGO:0030187 melatonin biosynthetic process IEA
 biological_processGO:0032259 methylation IEA
 biological_processGO:0046219 indolalkylamine biosynthetic process TAS
 cellular_componentGO:0005829 cytosol TAS
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0008171 O-methyltransferase activity IEA
 molecular_functionGO:0008172 S-methyltransferase activity TAS
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017096 acetylserotonin O-methyltransferase activity IEA
 molecular_functionGO:0042802 identical protein binding IPI
 molecular_functionGO:0042803 protein homodimerization activity IPI


Pathways (from Reactome)
Pathway description
Serotonin and melatonin biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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