ENSG00000197858


Homo sapiens

Features
Gene ID: ENSG00000197858
  
Biological name :GPAA1
  
Synonyms : glycosylphosphatidylinositol anchor attachment 1 / GPAA1 / O43292
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 8
Strand: 1
Band: q24.3
Gene start: 144082590
Gene end: 144086216
  
Corresponding Affymetrix probe sets: 201618_x_at (Human Genome U133 Plus 2.0 Array)   211060_x_at (Human Genome U133 Plus 2.0 Array)   215690_x_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000347206
Ensembl peptide - ENSP00000354316
Ensembl peptide - ENSP00000435132
Ensembl peptide - ENSP00000435119
Ensembl peptide - ENSP00000435024
Ensembl peptide - ENSP00000434544
Ensembl peptide - ENSP00000434485
Ensembl peptide - ENSP00000431233
NCBI entrez gene - 8733     See in Manteia.
OMIM - 603048
RefSeq - NM_003801
RefSeq Peptide - NP_003792
swissprot - E9PM94
swissprot - E9PM11
swissprot - E9PLV6
swissprot - E9PLG8
swissprot - E9PQ31
swissprot - O43292
swissprot - E9PPZ9
Ensembl - ENSG00000197858
  
Related genetic diseases (OMIM): 617810 - Glycosylphosphatidylinositol biosynthesis defect 15, 617810
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpaa1ENSDARG00000074571Danio rerio
 Gpaa1ENSMUSG00000022561Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007246  GPI transamidase component Gaa1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006506 GPI anchor biosynthetic process IEA
 biological_processGO:0006621 protein retention in ER lumen NAS
 biological_processGO:0016255 attachment of GPI anchor to protein TAS
 biological_processGO:0065003 protein-containing complex assembly NAS
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane TAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042765 GPI-anchor transamidase complex IEA
 molecular_functionGO:0003923 GPI-anchor transamidase activity NAS
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0015631 tubulin binding NAS
 molecular_functionGO:0034235 GPI anchor binding IMP


Pathways (from Reactome)
Pathway description
Attachment of GPI anchor to uPAR


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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