ENSG00000198089


Homo sapiens

Features
Gene ID: ENSG00000198089
  
Biological name :SFI1
  
Synonyms : A8K8P3 / SFI1 / SFI1 centrin binding protein
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 22
Strand: 1
Band: q12.2
Gene start: 31488688
Gene end: 31618586
  
Corresponding Affymetrix probe sets: 213431_x_at (Human Genome U133 Plus 2.0 Array)   214402_s_at (Human Genome U133 Plus 2.0 Array)   215699_x_at (Human Genome U133 Plus 2.0 Array)   36545_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000411793
Ensembl peptide - ENSP00000405541
Ensembl peptide - ENSP00000416931
Ensembl peptide - ENSP00000443025
Ensembl peptide - ENSP00000430488
Ensembl peptide - ENSP00000383145
Ensembl peptide - ENSP00000383146
Ensembl peptide - ENSP00000389364
Ensembl peptide - ENSP00000391339
Ensembl peptide - ENSP00000398871
Ensembl peptide - ENSP00000401199
Ensembl peptide - ENSP00000402679
NCBI entrez gene - 9814     See in Manteia.
OMIM - 612765
RefSeq - XM_017029162
RefSeq - XM_017029148
RefSeq - XM_017029149
RefSeq - XM_017029150
RefSeq - XM_017029151
RefSeq - XM_017029152
RefSeq - XM_017029153
RefSeq - XM_017029154
RefSeq - XM_017029155
RefSeq - XM_017029156
RefSeq - XM_017029157
RefSeq - XM_017029158
RefSeq - XM_017029159
RefSeq - XM_017029160
RefSeq - XM_017029161
RefSeq - NM_001007467
RefSeq - NM_001258325
RefSeq - NM_001258326
RefSeq - NM_001258327
RefSeq - NM_014775
RefSeq - XM_005261868
RefSeq - XM_006724390
RefSeq - XM_011530570
RefSeq - XM_011530571
RefSeq - XM_011530574
RefSeq - XM_011530575
RefSeq - XM_011530576
RefSeq - XM_011530577
RefSeq - XM_011530579
RefSeq - XM_011530580
RefSeq - XM_011530581
RefSeq - XM_011530582
RefSeq - XM_011530583
RefSeq - XM_011530587
RefSeq - XM_017029139
RefSeq - XM_017029140
RefSeq - XM_017029141
RefSeq - XM_017029142
RefSeq - XM_017029143
RefSeq - XM_017029144
RefSeq - XM_017029145
RefSeq - XM_017029146
RefSeq - XM_017029147
RefSeq Peptide - NP_001245254
RefSeq Peptide - NP_001245255
RefSeq Peptide - NP_001245256
RefSeq Peptide - NP_055590
RefSeq Peptide - NP_001007468
swissprot - H7BZF3
swissprot - H7C2F1
swissprot - X6RJF9
swissprot - A8K8P3
swissprot - E5RJU6
swissprot - D3YTJ2
swissprot - F8WBU4
swissprot - H0Y5I7
swissprot - H0Y836
Ensembl - ENSG00000198089
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 sfi1ENSDARG00000053992Danio rerio
 Sfi1ENSMUSG00000023764Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR030516  Protein SFI1 homologue


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle TAS
 biological_processGO:0010923 negative regulation of phosphatase activity IDA
 biological_processGO:0097711 ciliary basal body-plasma membrane docking TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005814 centriole IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0019902 phosphatase binding IDA


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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