ENSG00000205659


Homo sapiens

Features
Gene ID: ENSG00000205659
  
Biological name :LIN52
  
Synonyms : LIN52 / lin-52 DREAM MuvB core complex component / Q52LA3
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 14
Strand: 1
Band: q24.3
Gene start: 74084796
Gene end: 74201235
  
Corresponding Affymetrix probe sets: 228583_at (Human Genome U133 Plus 2.0 Array)   231959_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451812
Ensembl peptide - ENSP00000452513
NCBI entrez gene - 91750     See in Manteia.
RefSeq - XM_017021764
RefSeq - NM_001024674
RefSeq - XM_011537321
RefSeq - XM_011537322
RefSeq - XM_017021763
RefSeq - XM_011537320
RefSeq Peptide - NP_001019845
swissprot - Q52LA3
swissprot - G3V5T8
Ensembl - ENSG00000205659
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lin52ENSDARG00000070833Danio rerio
 LIN52ENSGALG00000020419Gallus gallus
 Lin52ENSMUSG00000085793Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR018737  Protein LIN52


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0051726 regulation of cell cycle TAS
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0070176 DRM complex IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Transcription of E2F targets under negative control by DREAM complex
Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1
G0 and Early G1
Polo-like kinase mediated events
Activation of E2F1 target genes at G1/S
Cyclin E associated events during G1/S transition
Cyclin A:Cdk2-associated events at S phase entry


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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contact: otassy@igbmc.fr