ENSG00000221988


Homo sapiens

Features
Gene ID: ENSG00000221988
  
Biological name :PPT2
  
Synonyms : palmitoyl-protein thioesterase 2 / PPT2 / Q9UMR5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 6
Strand: 1
Band: p21.32
Gene start: 32153441
Gene end: 32163680
  
Corresponding Affymetrix probe sets: 209490_s_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000364285
Ensembl peptide - ENSP00000378894
Ensembl peptide - ENSP00000409877
Ensembl peptide - ENSP00000398847
Ensembl peptide - ENSP00000395456
Ensembl peptide - ENSP00000320528
Ensembl peptide - ENSP00000354608
Ensembl peptide - ENSP00000364279
NCBI entrez gene - 9374     See in Manteia.
OMIM - 603298
RefSeq - NM_005155
RefSeq - NM_138717
RefSeq - NM_001204103
swissprot - G8JLL2
swissprot - A2ABN7
swissprot - Q9UMR5
swissprot - A2ABN6
swissprot - A0A1U9X8D2
Ensembl - ENSG00000221988
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppt2ENSDARG00000104542Danio rerio
 Ppt2ENSMUSG00000015474Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PPT2-EGFL8 / PPT2-EGFL8 readthrough (NMD candidate)ENSG0000025838884
PPT1 / P50897 / palmitoyl-protein thioesterase 1ENSG0000013123823


Protein motifs (from Interpro)
Interpro ID Name
 IPR000073  Alpha/beta hydrolase fold-1
 IPR002472  Palmitoyl protein thioesterase
 IPR029058  Alpha/Beta hydrolase fold
 IPR030295  Lysosomal thioesterase PPT2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0046949 fatty-acyl-CoA biosynthetic process TAS
 biological_processGO:0098734 macromolecule depalmitoylation IEA
 cellular_componentGO:0005764 lysosome NAS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043202 lysosomal lumen TAS
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IBA
 cellular_componentGO:0070062 extracellular exosome HDA
 molecular_functionGO:0008474 palmitoyl-(protein) hydrolase activity IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0016790 thiolester hydrolase activity NAS
 molecular_functionGO:0098599 palmitoyl hydrolase activity TAS


Pathways (from Reactome)
Pathway description
Fatty acyl-CoA biosynthesis


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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