ENSG00000241644


Homo sapiens

Features
Gene ID: ENSG00000241644
  
Biological name :INMT
  
Synonyms : indolethylamine N-methyltransferase / INMT / O95050
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: 1
Band: p14.3
Gene start: 30697985
Gene end: 30757602
  
Corresponding Affymetrix probe sets: 224061_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000013222
Ensembl peptide - ENSP00000386961
NCBI entrez gene - 11185     See in Manteia.
OMIM - 604854
RefSeq - NM_001199219
RefSeq - NM_006774
RefSeq Peptide - NP_001186148
RefSeq Peptide - NP_006765
swissprot - O95050
Ensembl - ENSG00000241644
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 zgc:64002ENSDARG00000086998Danio rerio
 InmtENSMUSG00000003477Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NNMT / P40261 / nicotinamide N-methyltransferaseENSG0000016674152
INMT-MINDY4 / INMT-MINDY4 readthrough (NMD candidate)ENSG0000025495946
PNMT / P11086 / phenylethanolamine N-methyltransferaseENSG0000014174435


Protein motifs (from Interpro)
Interpro ID Name
 IPR000940  Methyltransferase, NNMT/PNMT/TEMT
 IPR025820  Methyltransferase NNMT/PNMT/TEMT, conserved site
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009308 amine metabolic process IDA
 biological_processGO:0009636 response to toxic substance IEA
 biological_processGO:0032259 methylation IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 molecular_functionGO:0004790 thioether S-methyltransferase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030748 amine N-methyltransferase activity IEA
 molecular_functionGO:0102707 S-adenosyl-L-methionine:beta-alanine N-methyltransferase activity IEA


Pathways (from Reactome)
Pathway description
Methylation of MeSeH for excretion


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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