ENSG00000249115


Homo sapiens

Features
Gene ID: ENSG00000249115
  
Biological name :HAUS5
  
Synonyms : HAUS5 / HAUS augmin like complex subunit 5 / O94927
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 19
Strand: 1
Band: q13.12
Gene start: 35612744
Gene end: 35625349
  
Corresponding Affymetrix probe sets: 213053_at (Human Genome U133 Plus 2.0 Array)   213054_at (Human Genome U133 Plus 2.0 Array)   36888_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000466661
Ensembl peptide - ENSP00000475856
Ensembl peptide - ENSP00000475934
Ensembl peptide - ENSP00000439056
Ensembl peptide - ENSP00000467688
NCBI entrez gene - 23354     See in Manteia.
OMIM - 613432
RefSeq - XM_011526684
RefSeq - NM_015302
RefSeq Peptide - NP_056117
swissprot - O94927
swissprot - U3KQG4
swissprot - U3KQJ5
swissprot - K7EQ61
Ensembl - ENSG00000249115
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 haus5ENSDARG00000019156Danio rerio
 Haus5ENSMUSG00000078762Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR026215  HAUS complex subunit 5, metazoa
 IPR029131  HAUS augmin-like complex subunit 5


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle TAS
 biological_processGO:0007049 cell cycle IEA
 biological_processGO:0007098 centrosome cycle IEA
 biological_processGO:0010389 regulation of G2/M transition of mitotic cell cycle TAS
 biological_processGO:0051225 spindle assembly IEA
 biological_processGO:0051301 cell division IEA
 biological_processGO:0097711 ciliary basal body-plasma membrane docking TAS
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005874 microtubule IEA
 cellular_componentGO:0070652 HAUS complex IEA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
Regulation of PLK1 Activity at G2/M Transition
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
Anchoring of the basal body to the plasma membrane
AURKA Activation by TPX2


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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