ENSG00000249751


Homo sapiens

Features
Gene ID: ENSG00000249751
  
Biological name :ECSCR
  
Synonyms : ECSCR / endothelial cell surface expressed chemotaxis and apoptosis regulator / Q19T08
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 5
Strand: -1
Band: q31.2
Gene start: 139448556
Gene end: 139462743
  
Corresponding Affymetrix probe sets: 227779_at (Human Genome U133 Plus 2.0 Array)   227780_s_at (Human Genome U133 Plus 2.0 Array)   228339_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000479243
NCBI entrez gene - 641700     See in Manteia.
OMIM - 615736
RefSeq - NM_001293739
RefSeq - NM_001077693
RefSeq Peptide - NP_001071161
RefSeq Peptide - NP_001280668
swissprot - Q19T08
Ensembl - ENSG00000249751
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ecscrENSDARG00000087457Danio rerio
 ENSGALG00000024379Gallus gallus
 EcscrENSMUSG00000073599Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
AC142391.1ENSG00000279686100


Protein motifs (from Interpro)
Interpro ID Name
 IPR026247  Endothelial cell-specific chemotaxis regulator


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0016525 negative regulation of angiogenesis IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:1901800 positive regulation of proteasomal protein catabolic process IMP
 biological_processGO:2000353 positive regulation of endothelial cell apoptotic process IMP
 cellular_componentGO:0005654 nucleoplasm IDA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043231 intracellular membrane-bounded organelle IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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