ENSG00000253548


Homo sapiens

Features
Gene ID: ENSG00000253548
  
Biological name :PYDC2
  
Synonyms : PYDC2 / pyrin domain containing 2 / Q56P42
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 3
Strand: 1
Band: q28
Gene start: 191461163
Gene end: 191461456
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSP00000492367
NCBI entrez gene - 152138     See in Manteia.
OMIM - 615701
RefSeq - NM_001083308
RefSeq Peptide - NP_001076777
swissprot - Q56P42
Ensembl - ENSG00000253548
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
No match


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NLRP2B / P0DMW2 / NLR family pyrin domain containing 2BENSG0000021517437


Protein motifs (from Interpro)
Interpro ID Name
 IPR004020  DAPIN domain
 IPR011029  Death-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0009968 negative regulation of signal transduction IEA
 biological_processGO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway IMP
 biological_processGO:0032088 negative regulation of NF-kappaB transcription factor activity IMP
 biological_processGO:0045087 innate immune response IEA
 biological_processGO:0050713 negative regulation of interleukin-1 beta secretion IMP
 biological_processGO:0050728 negative regulation of inflammatory response IMP
 biological_processGO:1900226 negative regulation of NLRP3 inflammasome complex assembly IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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