ENSG00000258227


Homo sapiens

Features
Gene ID: ENSG00000258227
  
Biological name :CLEC5A
  
Synonyms : CLEC5A / C-type lectin domain containing 5A / Q9NY25
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: q34
Gene start: 141927357
Gene end: 141947007
  
Corresponding Affymetrix probe sets: 219890_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000449999
Ensembl peptide - ENSP00000392561
Ensembl peptide - ENSP00000395258
Ensembl peptide - ENSP00000414897
Ensembl peptide - ENSP00000446890
NCBI entrez gene - 23601     See in Manteia.
OMIM - 604987
RefSeq - XM_017011917
RefSeq - NM_001301167
RefSeq - NM_013252
RefSeq - XM_011515995
RefSeq - XM_017011915
RefSeq - XM_017011916
RefSeq Peptide - NP_001288096
RefSeq Peptide - NP_037384
swissprot - Q14DL9
swissprot - C9JPR7
swissprot - C9JCE4
swissprot - F8WCL0
swissprot - Q9NY25
swissprot - A4D1U7
Ensembl - ENSG00000258227
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000029035Gallus gallus
 Clec5aENSMUSG00000029915Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001304  C-type lectin-like
 IPR016186  C-type lectin-like/link domain superfamily
 IPR016187  C-type lectin fold
 IPR033992  Natural killer cell receptor-like, C-type lectin-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002076 osteoblast development ISS
 biological_processGO:0002376 immune system process IEA
 biological_processGO:0006968 cellular defense response TAS
 biological_processGO:0007165 signal transduction TAS
 biological_processGO:0016032 viral process IEA
 biological_processGO:0030099 myeloid cell differentiation IEA
 biological_processGO:0033033 negative regulation of myeloid cell apoptotic process IEA
 biological_processGO:0043066 negative regulation of apoptotic process ISS
 biological_processGO:0043312 neutrophil degranulation TAS
 biological_processGO:0045087 innate immune response TAS
 biological_processGO:0046718 viral entry into host cell IEA
 biological_processGO:0050715 positive regulation of cytokine secretion IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0005887 integral component of plasma membrane TAS
 cellular_componentGO:0009986 cell surface ISS
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0035579 specific granule membrane TAS
 cellular_componentGO:0070821 tertiary granule membrane TAS
 molecular_functionGO:0001618 virus receptor activity IDA
 molecular_functionGO:0030246 carbohydrate binding IEA


Pathways (from Reactome)
Pathway description
DAP12 interactions
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000011600 O43914 / TYROBP / TYRO protein tyrosine kinase binding protein  / reaction / complex






 

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