ENSGALG00000001141


Gallus gallus

Features
Gene ID: ENSGALG00000001141
  
Biological name :HES5
  
Synonyms : HES5 / hes family bHLH transcription factor 5
  
Possible biological names infered from orthology : P70120 / Q5TA89 / Transcription factor HES-5
  
Species: Gallus gallus
  
Chr. number: 21
Strand: 1
Band:
Gene start: 1416932
Gene end: 1418581
  
Corresponding Affymetrix probe sets: Gga.11242.1.S1_at (Chicken Array)   GgaAffx.23247.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000064351
Ensembl peptide - ENSGALP00000001713
NCBI entrez gene - 419392     See in Manteia.
RefSeq - NM_001012695
RefSeq Peptide - NP_001012713
swissprot - Q5D212
swissprot - A0A1L1RZR5
Ensembl - ENSGALG00000001141
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 her2ENSDARG00000038205Danio rerio
 HES5ENSG00000197921Homo sapiens
 Hes5ENSMUSG00000048001Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
hairy and enhancer of split 5-like ENSGALG0000000113661
ENSGALG0000002700254


Protein motifs (from Interpro)
Interpro ID Name
 IPR003650  Orange domain
 IPR011598  Myc-type, basic helix-loop-helix (bHLH) domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0007155 cell adhesion IEA
 biological_processGO:0007219 Notch signaling pathway IEA
 biological_processGO:0007224 smoothened signaling pathway IEA
 biological_processGO:0007420 brain development IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0014003 oligodendrocyte development IEA
 biological_processGO:0021537 telencephalon development IEA
 biological_processGO:0021781 glial cell fate commitment IEA
 biological_processGO:0021915 neural tube development IEA
 biological_processGO:0022010 central nervous system myelination IEA
 biological_processGO:0030513 positive regulation of BMP signaling pathway IEA
 biological_processGO:0031641 regulation of myelination IEA
 biological_processGO:0042491 inner ear auditory receptor cell differentiation IEA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0042668 auditory receptor cell fate determination IEA
 biological_processGO:0043010 camera-type eye development IEA
 biological_processGO:0045595 regulation of cell differentiation IEA
 biological_processGO:0045607 regulation of inner ear auditory receptor cell differentiation IEA
 biological_processGO:0045665 negative regulation of neuron differentiation IEA
 biological_processGO:0045747 positive regulation of Notch signaling pathway IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046427 positive regulation of JAK-STAT cascade IEA
 biological_processGO:0048469 cell maturation IEA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IEA
 biological_processGO:0048708 astrocyte differentiation IEA
 biological_processGO:0048712 negative regulation of astrocyte differentiation IEA
 biological_processGO:0048715 negative regulation of oligodendrocyte differentiation IEA
 biological_processGO:0050678 regulation of epithelial cell proliferation IEA
 biological_processGO:0050767 regulation of neurogenesis IEA
 biological_processGO:0051216 cartilage development IEA
 biological_processGO:0060122 inner ear receptor cell stereocilium organization IEA
 biological_processGO:0065003 protein-containing complex assembly IEA
 biological_processGO:0072049 comma-shaped body morphogenesis IEA
 biological_processGO:0072050 S-shaped body morphogenesis IEA
 biological_processGO:0072086 specification of loop of Henle identity IEA
 biological_processGO:0072282 metanephric nephron tubule morphogenesis IEA
 biological_processGO:0090162 establishment of epithelial cell polarity IEA
 biological_processGO:0097150 neuronal stem cell population maintenance IEA
 biological_processGO:2000737 negative regulation of stem cell differentiation IEA
 biological_processGO:2000981 negative regulation of inner ear receptor cell differentiation IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0001078 transcriptional repressor activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0046983 protein dimerization activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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