ENSGALG00000003641


Gallus gallus

Features
Gene ID: ENSGALG00000003641
  
Biological name :KAT6A
  
Synonyms : KAT6A / lysine acetyltransferase 6A
  
Possible biological names infered from orthology : Q92794
  
Species: Gallus gallus
  
Chr. number: 22
Strand: -1
Band:
Gene start: 2698595
Gene end: 2723390
  
Corresponding Affymetrix probe sets: Gga.11179.1.S1_s_at (Chicken Array)   Gga.15114.1.S1_at (Chicken Array)   Gga.15114.1.S1_s_at (Chicken Array)   Gga.5159.1.S1_at (Chicken Array)   GgaAffx.25917.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000055545
Ensembl peptide - ENSGALP00000005756
NCBI entrez gene - 426789     See in Manteia.
RefSeq - XM_424402
RefSeq - XM_015297376
swissprot - F1NT94
swissprot - A0A1D5PRL8
Ensembl - ENSGALG00000003641
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kat6aENSDARG00000018907Danio rerio
 KAT6AENSG00000083168Homo sapiens
 Kat6aENSMUSG00000031540Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KAT6B / lysine acetyltransferase 6B / Q8BRB7* / Q8WYB5* / Histone acetyltransferase KAT6B *ENSGALG0000000503554
KAT7 / histone acetyltransferase KAT7 / Q5SVQ0* / O95251* / lysine acetyltransferase 7* / K(lysine) acetyltransferase 7*ENSGALG0000000994411


Protein motifs (from Interpro)
Interpro ID Name
 IPR001965  Zinc finger, PHD-type
 IPR002717  Histone acetyltransferase domain, MYST-type
 IPR005818  Linker histone H1/H5, domain H15
 IPR011011  Zinc finger, FYVE/PHD-type
 IPR011991  ArsR-like helix-turn-helix domain
 IPR013083  Zinc finger, RING/FYVE/PHD-type
 IPR016181  Acyl-CoA N-acyltransferase
 IPR019787  Zinc finger, PHD-finger
 IPR031280  Histone acetyltransferase KAT6A


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006334 nucleosome assembly IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006473 protein acetylation IEA
 biological_processGO:0016573 histone acetylation IEA
 biological_processGO:0030099 myeloid cell differentiation IEA
 biological_processGO:0043966 histone H3 acetylation IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0048513 animal organ development IEA
 biological_processGO:0090398 cellular senescence IEA
 cellular_componentGO:0000786 nucleosome IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005730 nucleolus IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016605 PML body IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0070776 MOZ/MORF histone acetyltransferase complex IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003713 transcription coactivator activity IEA
 molecular_functionGO:0004402 histone acetyltransferase activity IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0016407 acetyltransferase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
HATs acetylate histones
Regulation of TP53 Activity through Acetylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000002013 MEAF6 / Q5ZIX3 / Chromatin modification-related protein MEAF6 / Q9HAF1* / Q2VPQ9* / MYST/Esa1 associated factor 6*  / complex
 ENSGALG00000006317 ING5 / inhibitor of growth protein 5 / Q8WYH8* / Q9D8Y8* / inhibitor of growth family member 5*  / complex
 ENSGALG00000033529 BRPF1 / bromodomain and PHD finger containing 1 / B2RRD7* / P55201* / Peregrin *  / complex
 ENSGALG00000045534 PML* / P29590* / Q60953* / Protein PML * / promyelocytic leukemia*  / complex






 

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