ENSGALG00000009147


Gallus gallus

Features
Gene ID: ENSGALG00000009147
  
Biological name :NCSTN
  
Synonyms : NCSTN / nicastrin precursor
  
Possible biological names infered from orthology : nicastrin / P57716 / Q92542
  
Species: Gallus gallus
  
Chr. number: 25
Strand: 1
Band:
Gene start: 1221813
Gene end: 1232680
  
Corresponding Affymetrix probe sets: Gga.9792.2.S1_at (Chicken Array)   GgaAffx.12618.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000014876
NCBI entrez gene - 426905     See in Manteia.
RefSeq - NM_001004413
RefSeq Peptide - NP_001004413
swissprot - H9KZL2
Ensembl - ENSGALG00000009147
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01110881.1ENSDARG00000103284Danio rerio
 NCSTNENSG00000162736Homo sapiens
 NcstnENSMUSG00000003458Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008710  Nicastrin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002262 myeloid cell homeostasis IEA
 biological_processGO:0006509 membrane protein ectodomain proteolysis IEA
 biological_processGO:0007220 Notch receptor processing IBA
 biological_processGO:0016485 protein processing IBA
 biological_processGO:0034205 amyloid-beta formation IEA
 biological_processGO:0042098 T cell proliferation IEA
 biological_processGO:0042982 amyloid precursor protein metabolic process IEA
 biological_processGO:0043085 positive regulation of catalytic activity IEA
 biological_processGO:0050435 amyloid-beta metabolic process IEA
 biological_processGO:0050673 epithelial cell proliferation IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0070765 gamma-secretase complex IEA
 molecular_functionGO:0004175 endopeptidase activity IEA


Pathways (from Reactome)
Pathway description
Nuclear signaling by ERBB4
Regulated proteolysis of p75NTR
EPH-ephrin mediated repulsion of cells
Neutrophil degranulation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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