ENSGALG00000029449


Gallus gallus

Features
Gene ID: ENSGALG00000029449
  
Biological name :RFC2
  
Synonyms : P53033 / Replication factor C subunit 2 / RFC2
  
Possible biological names infered from orthology : P35250 / Q9WUK4 / replication factor C (activator 1) 2
  
Species: Gallus gallus
  
Chr. number: 19
Strand: 1
Band:
Gene start: 2823486
Gene end: 2829770
  
Corresponding Affymetrix probe sets: Gga.883.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000044744
Ensembl peptide - ENSGALP00000063942
Ensembl peptide - ENSGALP00000060406
Ensembl peptide - ENSGALP00000058128
Ensembl peptide - ENSGALP00000052755
NCBI entrez gene - 396542     See in Manteia.
RefSeq - XM_015295698
RefSeq - NM_205530
RefSeq Peptide - NP_990861
swissprot - A0A1D5PYS3
swissprot - A0A1D5NWK4
swissprot - A0A1L1RYL3
swissprot - P53033
swissprot - A0A1L1RNN8
Ensembl - ENSGALG00000029449
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 rfc2ENSDARG00000014274Danio rerio
 RFC2ENSG00000049541Homo sapiens
 Rfc2ENSMUSG00000023104Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003593  AAA+ ATPase domain
 IPR003959  ATPase, AAA-type, core
 IPR008921  DNA polymerase III, clamp loader complex, gamma/delta/delta subunit, C-terminal
 IPR013748  Replication factor C, C-terminal
 IPR027417  P-loop containing nucleoside triphosphate hydrolase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000724 double-strand break repair via homologous recombination TAS
 biological_processGO:0006260 DNA replication IEA
 biological_processGO:0006261 DNA-dependent DNA replication IBA
 biological_processGO:0006281 DNA repair IBA
 biological_processGO:1900264 positive regulation of DNA-directed DNA polymerase activity IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005654 nucleoplasm TAS
 cellular_componentGO:0005663 DNA replication factor C complex IEA
 cellular_componentGO:0031390 Ctf18 RFC-like complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003689 DNA clamp loader activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0043142 single-stranded DNA-dependent ATPase activity IEA


Pathways (from Reactome)
Pathway description
Translesion synthesis by REV1
Recognition of DNA damage by PCNA-containing replication complex
Translesion Synthesis by POLH
Polymerase switching on the C-strand of the telomere
Activation of ATR in response to replication stress
Chk1-controlled and DNA-damage induced centrosome duplication
Homologous recombination repair of replication-dependent double-strand breaks
Nucleotide Excision Repair
PCNA-Dependent Long Patch Base Excision Repair
Translesion synthesis by POLK
Translesion synthesis by POLI
Termination of translesion DNA synthesis
HDR through Single Strand Annealing (SSA)
HDR through Homologous Recombination (HRR)
Processing of DNA double-strand break ends
Presynaptic phase of homologous DNA pairing and strand exchange
Gap-filling DNA repair synthesis and ligation in GG-NER
Dual Incision in GG-NER
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Polymerase switching


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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