ENSGALG00000037138


Gallus gallus

Features
Gene ID: ENSGALG00000037138
  
Biological name :KCNQ1
  
Synonyms : KCNQ1 / potassium voltage-gated channel subfamily Q member 1
  
Possible biological names infered from orthology : P51787 / P97414 / Potassium voltage-gated channel subfamily KQT member 1
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 13449733
Gene end: 13471369
  
Corresponding Affymetrix probe sets: GgaAffx.4023.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000052056
swissprot - A0A1D5PGY0
Ensembl - ENSGALG00000037138
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 kcnq1ENSDARG00000059798Danio rerio
 KCNQ1ENSG00000053918Homo sapiens
 Kcnq1ENSMUSG00000009545Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNQ5 / potassium voltage-gated channel subfamily Q member 5 / Q9JK45* / Q9NR82* / Potassium voltage-gated channel subfamily KQT member 5 *ENSGALG0000003724947
KCNQ2 / potassium voltage-gated channel subfamily Q member 2 / O43526* / potassium voltage-gated channel subfamily KQT member 2 isoform 13 *ENSGALG0000000582247
KCNQ3 / potassium voltage-gated channel subfamily Q member 3 / O43525* / Q8K3F6* / Potassium voltage-gated channel subfamily KQT member 3 *ENSGALG0000003762642
KCNQ4 / potassium voltage-gated channel subfamily Q member 4 / P56696* / Q9JK97* / Potassium voltage-gated channel subfamily KQT member 4 *ENSGALG0000003870842


Protein motifs (from Interpro)
Interpro ID Name
 IPR003937  Potassium channel, voltage dependent, KCNQ
 IPR005821  Ion transport domain
 IPR005827  Potassium channel, voltage dependent, KCNQ1
 IPR028325  Voltage-gated potassium channel


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006349 regulation of gene expression by genetic imprinting IEA
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0010460 positive regulation of heart rate IEA
 biological_processGO:0016458 gene silencing IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0048839 inner ear development IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060048 cardiac muscle contraction IEA
 biological_processGO:0060306 regulation of membrane repolarization IEA
 biological_processGO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization IEA
 biological_processGO:0060372 regulation of atrial cardiac muscle cell membrane repolarization IEA
 biological_processGO:0060452 positive regulation of cardiac muscle contraction IEA
 biological_processGO:0060453 regulation of gastric acid secretion IEA
 biological_processGO:0070293 renal absorption IEA
 biological_processGO:0071320 cellular response to cAMP IEA
 biological_processGO:0071435 potassium ion export IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:0072358 cardiovascular system development IEA
 biological_processGO:0086005 ventricular cardiac muscle cell action potential IEA
 biological_processGO:0086009 membrane repolarization IEA
 biological_processGO:0086011 membrane repolarization during action potential IEA
 biological_processGO:0086013 membrane repolarization during cardiac muscle cell action potential IEA
 biological_processGO:0086014 atrial cardiac muscle cell action potential IEA
 biological_processGO:0086091 regulation of heart rate by cardiac conduction IEA
 biological_processGO:0097623 potassium ion export across plasma membrane IEA
 biological_processGO:0098914 membrane repolarization during atrial cardiac muscle cell action potential IEA
 biological_processGO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential IEA
 biological_processGO:1901381 positive regulation of potassium ion transmembrane transport IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005764 lysosome IEA
 cellular_componentGO:0005769 early endosome IEA
 cellular_componentGO:0005770 late endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane IEA
 cellular_componentGO:0034702 ion channel complex IEA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005251 delayed rectifier potassium channel activity IEA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005546 phosphatidylinositol-4,5-bisphosphate binding IEA
 molecular_functionGO:0008157 protein phosphatase 1 binding IEA
 molecular_functionGO:0015271 outward rectifier potassium channel activity IEA
 molecular_functionGO:0034236 protein kinase A catalytic subunit binding IEA
 molecular_functionGO:0034237 protein kinase A regulatory subunit binding IEA
 molecular_functionGO:0044325 ion channel binding IEA
 molecular_functionGO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization IEA
 molecular_functionGO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization IEA
 molecular_functionGO:0097110 scaffold protein binding IEA
 molecular_functionGO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels
Phase 3 - rapid repolarisation
Phase 2 - plateau phase


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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