ENSGALG00000042836


Gallus gallus

Features
Gene ID: ENSGALG00000042836
  
Biological name :KCNH2
  
Synonyms : KCNH2 / potassium voltage-gated channel subfamily H member 2
  
Possible biological names infered from orthology : Q12809
  
Species: Gallus gallus
  
Chr. number: 2
Strand: 1
Band:
Gene start: 322430
Gene end: 330338
  
Corresponding Affymetrix probe sets:
  
Cross references: Ensembl peptide - ENSGALP00000044315
swissprot - A0A1D5NVE1
Ensembl - ENSGALG00000042836
  
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 CABZ01076968.1ENSDARG00000106473Danio rerio
 kcnh2aENSDARG00000029881Danio rerio
 KCNH2ENSG00000055118Homo sapiens
 Kcnh2ENSMUSG00000038319Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
KCNH6 / potassium voltage-gated channel subfamily H member 6 ENSGALG0000000050584
ENSGALG0000003854382
KCNH4 / potassium voltage-gated channel subfamily H member 4 / Q9UQ05*ENSGALG0000000335447
KCNH8 / potassium voltage-gated channel subfamily H member 8 / Q96L42*ENSGALG0000001126246
KCNH1* / O95259* / AC092017.3* / AL590132.1* / potassium voltage-gated channel subfamily H member 1*ENSGALG0000000987744
KCNH5 / potassium voltage-gated channel subfamily H member 5 / Q8NCM2* / Q920E3*ENSGALG0000001185836
KCNH7* / Q9ER47* / Q9NS40* / potassium voltage-gated channel subfamily H member 7*ENSGALG000000359380


Protein motifs (from Interpro)
Interpro ID Name
 IPR003938  Potassium channel, voltage-dependent, EAG/ELK/ERG
 IPR003967  Potassium channel, voltage-dependent, ERG
 IPR005821  Ion transport domain
 IPR030172  Potassium voltage-gated channel subfamily H member 6


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0034220 ion transmembrane transport IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0055075 potassium ion homeostasis IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0060048 cardiac muscle contraction IEA
 biological_processGO:0060306 regulation of membrane repolarization IEA
 biological_processGO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization IEA
 biological_processGO:0071435 potassium ion export IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:0086005 ventricular cardiac muscle cell action potential IEA
 biological_processGO:0086009 membrane repolarization IEA
 biological_processGO:0086010 membrane depolarization during action potential IEA
 biological_processGO:0086011 membrane repolarization during action potential IEA
 biological_processGO:0086013 membrane repolarization during cardiac muscle cell action potential IEA
 biological_processGO:0086091 regulation of heart rate by cardiac conduction IEA
 biological_processGO:0097623 potassium ion export across plasma membrane IEA
 biological_processGO:0098915 membrane repolarization during ventricular cardiac muscle cell action potential IEA
 biological_processGO:1901379 regulation of potassium ion transmembrane transport IEA
 biological_processGO:1901380 negative regulation of potassium ion transmembrane transport IEA
 biological_processGO:1901381 positive regulation of potassium ion transmembrane transport IEA
 biological_processGO:1902303 negative regulation of potassium ion export IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 cellular_componentGO:1902937 inward rectifier potassium channel complex IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005242 inward rectifier potassium channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IEA
 molecular_functionGO:0005251 delayed rectifier potassium channel activity IEA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0055131 C3HC4-type RING finger domain binding IEA
 molecular_functionGO:0097110 scaffold protein binding IEA
 molecular_functionGO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization IEA


Pathways (from Reactome)
Pathway description
Voltage gated Potassium channels
Phase 3 - rapid repolarisation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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