ENSMUSG00000000194


Mus musculus

Features
Gene ID: ENSMUSG00000000194
  
Biological name :Gpr107
  
Synonyms : Gpr107 / G protein-coupled receptor 107 / Q8BUV8
  
Possible biological names infered from orthology : Q5VW38
  
Species: Mus musculus
  
Chr. number: 2
Strand: 1
Band: B
Gene start: 31152316
Gene end: 31218775
  
Corresponding Affymetrix probe sets: 10471108 (MoGene1.0st)   1434086_at (Mouse Genome 430 2.0 Array)   1444775_at (Mouse Genome 430 2.0 Array)   1454828_at (Mouse Genome 430 2.0 Array)   1459788_at (Mouse Genome 430 2.0 Array)   1460094_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000056739
NCBI entrez gene - 277463     See in Manteia.
MGI - MGI:2139054
RefSeq - NM_178760
RefSeq Peptide - NP_848875
swissprot - Q148Z6
swissprot - Q8BUV8
Ensembl - ENSMUSG00000000194
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gpr107ENSDARG00000103200Danio rerio
 GPR107ENSGALG00000004052Gallus gallus
 GPR107ENSG00000148358Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gpr108 / Q91WD0 / G protein-coupled receptor 108 / Q9NPR9*ENSMUSG0000000582349


Protein motifs (from Interpro)
Interpro ID Name
 IPR009637  Lung seven transmembrane receptor-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0072583 clathrin-dependent endocytosis IMP
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005769 early endosome IDA
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030136 clathrin-coated vesicle IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0032050 clathrin heavy chain binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001698 reduced embryo size "smaller proportions of embryo compared to littermates" [J:61790]
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Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

 MP:0002599 increased mean platelet volume "increased content of platelet cells over the norm" [cml:Cathleen M. Lutz, Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr1tm1.1(KOMP)Vlcg/Fgfr1+
Genetic Background: C57BL/6N-Fgfr1tm1.1(KOMP)Vlcg/Ucd

 MP:0005554 decreased circulating creatinine level "less than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
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Allelic Composition: Fgfr1tm1.1(KOMP)Vlcg/Fgfr1+
Genetic Background: C57BL/6N-Fgfr1tm1.1(KOMP)Vlcg/Ucd

 MP:0008546 abnormal vesicle-mediated transport "anomaly in the directed movement of substances, either within a vesicle or in the vesicle membrane, into, out of or within a cell" [GO:0016192]
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Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

 MP:0008935 decreased mean platelet volume "reduced average content of platelet cells over normal" [MGI:mberry "Melissa Berry, Genetics Resources Curator"]
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Allelic Composition: Fgfr1tm1.1(KOMP)Vlcg/Fgfr1+
Genetic Background: C57BL/6N-Fgfr1tm1.1(KOMP)Vlcg/Ucd

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
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Allelic Composition: Scn8a9J/Scn8a9J
Genetic Background: B6J.C-Scn8a9J/Mm

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Glycam1tm1.1(KOMP)Vlcg/Glycam1tm1.1(KOMP)Vlcg
Genetic Background: C57BL/6N-Glycam1tm1.1(KOMP)Vlcg/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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