Manteia - Molecule gene

ENSMUSG00000000374

Mus musculus

Features

Gene ID:	ENSMUSG00000000374

Biological name :	Trappc10

Synonyms :	Trappc10

Possible biological names infered from orthology :	FP565260.7 / P48553 / trafficking protein particle complex 10

Species:	Mus musculus

Chr. number:	10
Strand:	-1
Band:	C1
Gene start:	78186725
Gene end:	78244641

Corresponding Affymetrix probe sets:	10370446 (MoGene1.0st) 1435430_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000000384 Ensembl peptide - ENSMUSP00000152048 Ensembl peptide - ENSMUSP00000151489 NCBI entrez gene - 216131 See in Manteia. MGI - MGI:1336209 RefSeq - NM_001081055 RefSeq Peptide - NP_001074524 swissprot - A0A1W2P8E9 swissprot - A0A1W2P717 swissprot - F8VQF9 Ensembl - ENSMUSG00000000374

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
trappc10	ENSDARG00000098118	Danio rerio
	ENSGALG00000022804	Gallus gallus
FP565260.7	ENSG00000280433	Homo sapiens
P48553	ENSG00000160218	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name

ID

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR008972	Cupredoxin
IPR022233	TRAPP II complex, TRAPPC10

Gene Ontology (GO)

Type

GO ID

Term

Ev.Code

No match

Pathways (from Reactome)

Pathway description

COPII-mediated vesicle transport

RAB GEFs exchange GTP for GDP on RABs

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000111	cleft palate	"congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Dnah5^b2b2570Clo/Dnah5^b2b2570Clo Genetic Background: C57BL/6J-Dnah5^b2b2570Clo
MP:0000276	right ventricle hypertrophy	"increased size of the right ventricle" [J:33629]	Show Allelic Composition: Hoxa5^tm1.1Ljea/Hoxa5^tm1.1Ljea,Tg(Hoxa5-cre)447BLjea/0 Genetic Background: involves: 129/Sv * C57BL/6 * CBA * SJL
MP:0001293	anophthalmia	"congenital absence of all tissues of the eyes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CML, J:71979]	Show Allelic Composition: Hoxa5^tm1.1Ljea/Hoxa5^tm1.1Ljea,Tg(Hoxa5-cre)447BLjea/0 Genetic Background: involves: 129/Sv * C57BL/6 * CBA * SJL
MP:0001297	microphthalmia	"reduced average size of the eyes" [J:18048]	Show Allelic Composition: Dnah5^b2b2570Clo/Dnah5^b2b2570Clo Genetic Background: C57BL/6J-Dnah5^b2b2570Clo
MP:0001539	decreased number of caudal vertebrae	"reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Tmem79^{tm1.1(KOMP)Wtsi}/Tmem79^{tm1.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Tmem79^{tm1.1(KOMP)Wtsi}/J
MP:0001625	cardiac hypertrophy	"an increase in size of the cardiac tissue, not due to increased cell number " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Dnah5^b2b2570Clo/Dnah5^b2b2570Clo Genetic Background: C57BL/6J-Dnah5^b2b2570Clo
MP:0001823	thymus hypoplasia	"small size due to reduced cell number in the thymus" [J:23255]	Show Allelic Composition: Hoxa5^tm1.1Ljea/Hoxa5^tm1.1Ljea,Tg(Hoxa5-cre)447BLjea/0 Genetic Background: involves: 129/Sv * C57BL/6 * CBA * SJL
MP:0001890	anencephaly	"absence of the bones of the cranial vault and absent or rudimentary cerebral and cerebellar hemispheres, brainstem, and basal ganglia" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:31571]	Show Allelic Composition: Hoxa5^tm1.1Ljea/Hoxa5^tm1.1Ljea,Tg(Hoxa5-cre)447BLjea/0 Genetic Background: involves: 129/Sv * C57BL/6 * CBA * SJL
MP:0002625	left ventricle hypertrophy	"increased size of the left ventricle" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Hoxa5^tm1.1Ljea/Hoxa5^tm1.1Ljea,Tg(Hoxa5-cre)447BLjea/0 Genetic Background: involves: 129/Sv * C57BL/6 * CBA * SJL
MP:0002639	micrognathia	"abnormally reduced size of the jaws, especially of the mandible" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Dnah5^b2b2570Clo/Dnah5^b2b2570Clo Genetic Background: C57BL/6J-Dnah5^b2b2570Clo
MP:0003050	abnormal sacral vertebrae morphology	"malformation of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Tmem79^{tm1.1(KOMP)Wtsi}/Tmem79^{tm1.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Tmem79^{tm1.1(KOMP)Wtsi}/J
MP:0004647	decreased lumbar vertebrae number	"reduced number of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MESH:National Library of Medicine_Medical Subject Headings]	Show Allelic Composition: Tmem79^{tm1.1(KOMP)Wtsi}/Tmem79^{tm1.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Tmem79^{tm1.1(KOMP)Wtsi}/J
MP:0005157	holoprosencephaly	"presence of a single forebrain hemisphere or lobe; often accompanied by a deficit in median facial development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83058]	Show Allelic Composition: Hoxa5^tm1.1Ljea/Hoxa5^tm1.1Ljea,Tg(Hoxa5-cre)447BLjea/0 Genetic Background: involves: 129/Sv * C57BL/6 * CBA * SJL
MP:0010101	increased sacral vertebrae number	"increase of any or all of the four bony segments of the spine located posterior to the lumbar vertebrae and anterior to the caudal vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Tmem79^{tm1.1(KOMP)Wtsi}/Tmem79^{tm1.1(KOMP)Wtsi} Genetic Background: C57BL/6N-Tmem79^{tm1.1(KOMP)Wtsi}/J
MP:0010402	ventricular septal defect	"abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]	Show Allelic Composition: Hoxa5^tm1.1Ljea/Hoxa5^tm1.1Ljea,Tg(Hoxa5-cre)447BLjea/0 Genetic Background: involves: 129/Sv * C57BL/6 * CBA * SJL Allelic Composition: Trappc10^b2b2613Clo/Trappc10^b2b2613Clo Genetic Background: C57BL/6J-Trappc10^b2b2613Clo
MP:0010412	atrioventricular septal defect	"defects in the thin membranous structure between the right atrium and left ventricle that arise from faulty development of the embryonic endocardial cushions; the spectrum ranges from a primum atrial septal defect and cleft mitral valve, known as a partial atrioventricular septal defect (partial AVSD), to defects of both the primum atrial septum and inlet ventricular septum and the presence of a common atrioventricular valve, referred to as complete atrioventricular septal defect (complete AVSD)" [http://emedicine.medscape.com]	Show Allelic Composition: Hoxa5^tm1.1Ljea/Hoxa5^tm1.1Ljea,Tg(Hoxa5-cre)447BLjea/0 Genetic Background: involves: 129/Sv * C57BL/6 * CBA * SJL Allelic Composition: Trappc10^b2b2613Clo/Trappc10^b2b2613Clo Genetic Background: C57BL/6J-Trappc10^b2b2613Clo
MP:0010420	muscular ventricular septal defect	"abnormal communications between the two lower chambers of the heart, involving the muscular septum and often occurring as multiple communications, and includes central muscular or midmuscular, apical, or marginal communications when the defect is along the RV-septal junction; any single defect observed from the LV aspect may have several openings on the RV aspect" [http://emedicine.medscape.com]	Show Allelic Composition: Trappc10^b2b2613Clo/Trappc10^b2b2613Clo Genetic Background: C57BL/6J-Trappc10^b2b2613Clo

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr