| MP:0000284 | double outlet right ventricle | "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0000841 | abnormal hindbrain morphology | "malformed caudal region of the brain; includes cerebellum, pons and medulla oblongata" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0000848 | abnormal pons | "malformed band of nerve fibers in the brain connecting the medulla oblongata and the mesencephalon; this region conveys information about movement from the cerebral hemisphere to the cerebellum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:1776, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0000914 | exencephaly | "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0000923 | abnormal roof plate morphology | "malformation or absence of a transient group of neuroepithelial cells located at the dorsal midline of the neural tube that profoundly influences the development of the vertebrate central nervous system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0000928 | incomplete cephalic closure | "arrest of the fusion of the cephalic neural folds" [J:12622] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0001575 | cyanosis | "a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0001890 | anencephaly | "absence of the bones of the cranial vault and absent or rudimentary cerebral and cerebellar hemispheres, brainstem, and basal ganglia" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:31571] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0003052 | omphalocele | "protrusion of abdominal viscera at the base of the umbilical cord, with a covering membranous sac of peritoneum-amnion" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003, ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0004110 | transposition of great arteries | "cardiovascular malformation in which the aorta arises from the right ventricle while the pulmonary artery arises from the left ventricle" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0009264 | failure of eyelid fusion | "the upper and lower thin folds of skin and muscle that cover the exposed portion of the eye do not fuse together during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0009888 | palatal shelves fail to meet at midline | "polarized growth towards the midline following palatal shelf elevation does not occur" [PMID:16942766] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0009890 | cleft secondary palate | "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0010402 | ventricular septal defect | "abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0011256 | abnormal neural fold morphology | "any structural anomaly of the elevated margins of the neural groove" [ISBN:0-683-40008-8] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0011380 | enlarged brain ventricle | "increased size of one or more of the four communicating cavities within the brain that are continuous with the central canal of the spinal cord" [MGI:smb] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0012261 | increased hindbrain apoptosis | "increase in the number of cells of the hindbrain undergoing programmed cell death" [MGI:anna] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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| MP:0012525 | abnormal rhombic lip morphology | "any structural anomaly of the posterior section of the developing metencephalon recognized transiently within the vertebrate embryo; the rhombic lip extends posteriorly from the roof of the fourth ventricle to dorsal neuroepithelial cell and can be divided into eight structural units based on rhombomeres 1-8 (r1-r8), recognized at early stages of hindbrain development; producing granule cells and five brainstem nuclei, the rhombic lip plays an important role in developing a complex cerebellar neural system" [MGI:anna] |
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Allelic Composition: Igf1rtm1Jcbr/Igf1rtm1Jcbr,Tg(Fabp4-cre)1Abel/?
Genetic Background: involves: C57BL/6 * FVB/N
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