ENSMUSG00000001100


Mus musculus

Features
Gene ID: ENSMUSG00000001100
  
Biological name :Poldip2
  
Synonyms : Poldip2 / Polymerase delta-interacting protein 2 / Q91VA6
  
Possible biological names infered from orthology : DNA polymerase delta interacting protein 2 / Q9Y2S7
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B5
Gene start: 78512193
Gene end: 78522736
  
Corresponding Affymetrix probe sets: 10379204 (MoGene1.0st)   1422732_at (Mouse Genome 430 2.0 Array)   1450727_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000001127
Ensembl peptide - ENSMUSP00000127708
NCBI entrez gene - 67811     See in Manteia.
MGI - MGI:1915061
RefSeq - NM_026389
RefSeq Peptide - NP_080665
swissprot - F6SQH7
swissprot - Q91VA6
Ensembl - ENSMUSG00000001100
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 poldip2ENSDARG00000092305Danio rerio
 POLDIP2ENSGALG00000003211Gallus gallus
 Q9Y2S7ENSG00000004142Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR007474  ApaG domain
 IPR011722  Hemimethylated DNA-binding domain
 IPR036623  Hemimethylated DNA-binding domain superfamily
 IPR036767  ApaG domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016242 negative regulation of macroautophagy IMP
 biological_processGO:0045931 positive regulation of mitotic cell cycle IMP
 biological_processGO:0070584 mitochondrion morphogenesis IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0042645 mitochondrial nucleoid IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0030674 protein binding, bridging ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000230 abnormal blood pressure "altered tension of the blood within the systemic arteries" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hdac3tm1.1Laz/Hdac3tm1.1Laz
Genetic Background: involves: C57BL/6

 MP:0000250 abnormal vasoconstriction "anomalous narrowing of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Hdac3tm1.1Laz/Hdac3tm1.1Laz
Genetic Background: involves: C57BL/6

 MP:0000272 abnormal aorta morphology "structural anomaly of the main trunk of the systemic arteries" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Hdac3tm1.1Laz/Hdac3tm1.1Laz
Genetic Background: involves: C57BL/6

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Hdac3tm1.1Laz/Hdac3tm1.1Laz
Genetic Background: involves: C57BL/6

 MP:0001613 abnormal vasodilation "anomalous widening of the lumen of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Hdac3tm1.1Laz/Hdac3tm1.1Laz
Genetic Background: involves: C57BL/6

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Hdac3tm1.1Laz/Hdac3tm1.1Laz
Genetic Background: involves: C57BL/6

 MP:0009862 abnormal aorta elastic tissue morphology "any structural anomaly of the dense connective tissue which contains predominantly elastic fibers and is found in the tunica media of the aorta wall" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hdac3tm1.1Laz/Hdac3tm1.1Laz
Genetic Background: involves: C57BL/6

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Hdac3tm1.1Laz/Hdac3tm1.1Laz
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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