ENSMUSG00000001134


Mus musculus

Features
Gene ID: ENSMUSG00000001134
  
Biological name :Uxt
  
Synonyms : Q9WTZ0 / ubiquitously expressed transcript / Uxt
  
Possible biological names infered from orthology : Q9UBK9 / ubiquitously expressed prefoldin like chaperone
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: A1.3
Gene start: 20941722
Gene end: 20962017
  
Corresponding Affymetrix probe sets: 10432509 (MoGene1.0st)   10458428 (MoGene1.0st)   10603878 (MoGene1.0st)   1418986_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115342
NCBI entrez gene - 22294     See in Manteia.
MGI - MGI:1277988
RefSeq - XM_017318462
RefSeq - NM_013840
RefSeq - XM_006527602
RefSeq Peptide - NP_038868
swissprot - Q9WTZ0
Ensembl - ENSMUSG00000001134
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 uxtENSDARG00000019339Danio rerio
 UXTENSG00000126756Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003994  Ubiquitously expressed transcript protein UXT
 IPR004127  Prefoldin alpha-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0000226 microtubule cytoskeleton organization ISS
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007098 centrosome cycle ISS
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0000930 gamma-tubulin complex IEA
 cellular_componentGO:0005634 nucleus IBA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005815 microtubule organizing center IEA
 cellular_componentGO:0005856 cytoskeleton ISS
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0048487 beta-tubulin binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Mecp2em1Dkatz/Y,Tyrc-ch/Tyrc-ch
Genetic Background: FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Mecp2em1Dkatz/Y,Tyrc-ch/Tyrc-ch
Genetic Background: FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mecp2em1Dkatz/Y,Tyrc-ch/Tyrc-ch
Genetic Background: FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Mecp2em1Dkatz/Y,Tyrc-ch/Tyrc-ch
Genetic Background: FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Mecp2em1Dkatz/Y,Tyrc-ch/Tyrc-ch
Genetic Background: FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Mecp2em1Dkatz/Y,Tyrc-ch/Tyrc-ch
Genetic Background: FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J

Allelic Composition: Uxttm1.2Sklo/Uxt+
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0011750 abnormal seminiferous tubule epithelium morphology "any structural anomaly of the stratified epithelial lining of the seminiferous tubules, consisting of the developing spermatozoa and the supporting Sertoli cells, which are tall, columnar type cells that line the tubule" [MGI:csmith]
Show

Allelic Composition: Mecp2em1Dkatz/Y,Tyrc-ch/Tyrc-ch
Genetic Background: FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J

 MP:0014052 increased male germ cell apoptosis "greater number of male germs cells that undergo programmed cell death" [MGI:csmith]
Show

Allelic Composition: Mecp2em1Dkatz/Y,Tyrc-ch/Tyrc-ch
Genetic Background: FVB.Cg-Pde6b+ Tyrc-ch Mecp2em1Dkatz/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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