| MP:0000820 | abnormal choroid plexus morphology | "malformed or absent fringe of the tela choroidea of the cerebral ventricles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0000827 | dilated third ventricle | "enlarged narrow cleft inferior to the corpus callosum, within the diencephalon, between the paired thalami; its floor is formed by the hypothalamus, its anterior wall by the lamina terminalis, and its roof by ependyma; it communicates with the fourth ventricle by the cerebral aqueduct, and with the lateral ventricles by the interventricular foramina" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0000852 | small cerebellum | "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0000880 | decreased Purkinje cell number | "fewer than normal neuronal cells that are located in the interface of the molecular and granular layers of the cerebellar cortex" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:45302] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0001004 | abnormal photoreceptor morphology | "structural or developmental anomaly of the receptors sensitive to light " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0001147 | small testis | "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0001325 | abnormal retina morphology | "structural or developmental anomaly of the thin layer of neural tissue lining the back of the eyeball which contains visual receptors " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0001393 | ataxia | "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0001891 | hydroencephaly | "excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0002175 | low brain weight | "lower than average weight of the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0002687 | oligozoospermia | "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0003633 | abnormal nervous system physiology | |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0003729 | abnormal photoreceptor outer segments | "malformation/anomalous structure of the photoreceptor layer which contains stacks of membranous discs that are rich in the visual pigment rhodopsin " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0005551 | abnormal eye electrophysiology | "abnormal function of the eye as determined through electrophysiological recordings from single cells or summary recordings from multiple cells (e.g. electroretinogram)" [NMF:Stephanie Pretel, Neuroscience Mutagenesis Facility Curator] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0006072 | abnormal retinal apoptosis | "increase or decrease in the number of cells in the retina undergoing programmed cell death" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92622:] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0008028 | pregnancy-related premature death | "death occuring before the normal life span of an organism, occuring during pregnancy, parturition or lactation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:hdene "Howard Dene, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0008450 | retinal photoreceptor degeneration | "a retrogressive impairment of function or destruction of a cell specialized to detect and transduce light, including rods and cones of the retina" [MESH:A08.663.650.650, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0008511 | thin retinal inner nuclear layer | "reduced thickness of the retinal layer which contains the cell bodies of bipolar, horizontal, and amacrine cells" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0008515 | thin retinal outer nuclear layer | "reduced thickness of the retinal layer that contains the nuclei and cell bodies of rods and cones" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0008582 | short photoreceptor inner segment | "decreased length of the photoreceptor region which contains the machinery of the cell (mitochondria, golgi, endoplasmic reticulum, etc) and where opsin molecules are assembled and passed to be part of the outer segment region" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0008586 | disorganized photoreceptor outer segment | "derangement of the pattern of the photoreceptor region that is rich in the visual pigment rhodopsin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0008587 | short photoreceptor outer segment | "decreased length of the photoreceptor region that is rich in the visual pigment rhodopsin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0008995 | early reproductive senescence | "loss of reproductive capacity occurring at an earlier than expected age" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0009325 | necrospermia | "condition in which spermatozoa in seminal fluid are dead or motionless" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0010236 | abnormal retina outer limiting membrane morphology | "any structural anomaly of the row of junctional complexes between the plasma membranes of rod segments and the Muller glia cells; this barrier separates the layer of inner and outer segments of the rods and cones from the outer nuclear layer and forms a blood-retina barrier" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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| MP:0011056 | abnormal brain ependyma motile cilium morphology | "any structural anomaly of the tiny, motile hair-like projections from the epithelial cells that line the ventricles in the brain, which beat in concert and to move cerebrospinal fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dicer1tm1Bdh/Dicer1+,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * CBA/J
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