ENSMUSG00000001366


Mus musculus

Features
Gene ID: ENSMUSG00000001366
  
Biological name :Fbxo9
  
Synonyms : F-box only protein 9 / Fbxo9 / Q8BK06
  
Possible biological names infered from orthology : F-box protein 9 / Q9UK97
  
Species: Mus musculus
  
Chr. number: 9
Strand: -1
Band: E1
Gene start: 78081499
Gene end: 78109065
  
Corresponding Affymetrix probe sets: 10595126 (MoGene1.0st)   1417480_at (Mouse Genome 430 2.0 Array)   1432211_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125381
Ensembl peptide - ENSMUSP00000001402
Ensembl peptide - ENSMUSP00000082419
Ensembl peptide - ENSMUSP00000123807
NCBI entrez gene - 71538     See in Manteia.
MGI - MGI:1918788
RefSeq - NM_001081490
RefSeq - NM_023605
RefSeq Peptide - NP_001074959
RefSeq Peptide - NP_076094
swissprot - E0CYX8
swissprot - Q8BK06
Ensembl - ENSMUSG00000001366
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fbxo9ENSDARG00000011055Danio rerio
 FBXO9ENSGALG00000016320Gallus gallus
 FBXO9ENSG00000112146Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001810  F-box domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR036047  F-box-like domain superfamily
 IPR036181  MIT domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0016567 protein ubiquitination ISO
 biological_processGO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process ISO
 biological_processGO:0032006 regulation of TOR signaling ISS
 biological_processGO:0045087 innate immune response IMP
 biological_processGO:0045444 fat cell differentiation IMP
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0019005 SCF ubiquitin ligase complex ISO
 molecular_functionGO:0004842 ubiquitin-protein transferase activity ISO
 molecular_functionGO:0005515 protein binding IEA


Pathways (from Reactome)
Pathway description
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001402 hypoactivity "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289]
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Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

 MP:0001556 increased circulating HDL cholesterol level "higher than average level of high density lipoprotein in the blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47439]
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Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

 MP:0002768 small adrenal glands "reduced size of endocrine glands located above the kidneys responsible for hormone and epinephrine secretion" [J:78062]
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Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

 MP:0005642 decreased mean corpuscular hemoglobin concentration "less than the normal Hgb/Hct; the average hemoglobin concentration in a given volume of packed red cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:8936]
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Allelic Composition: Faddtm1e.1(KOMP)Wtsi/Faddtm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Faddtm1e.1(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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