ENSMUSG00000001524


Mus musculus

Features
Gene ID: ENSMUSG00000001524
  
Biological name :Gtf2h4
  
Synonyms : general transcription factor II H, polypeptide 4 / Gtf2h4 / O70422
  
Possible biological names infered from orthology : general transcription factor IIH subunit 4 / Q92759
  
Species: Mus musculus
  
Chr. number: 17
Strand: -1
Band: B1
Gene start: 35667730
Gene end: 35673739
  
Corresponding Affymetrix probe sets: 10450564 (MoGene1.0st)   1417093_a_at (Mouse Genome 430 2.0 Array)   1437163_x_at (Mouse Genome 430 2.0 Array)   1437368_at (Mouse Genome 430 2.0 Array)   1448585_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000124060
Ensembl peptide - ENSMUSP00000124683
Ensembl peptide - ENSMUSP00000124458
Ensembl peptide - ENSMUSP00000124335
Ensembl peptide - ENSMUSP00000124103
Ensembl peptide - ENSMUSP00000001565
NCBI entrez gene - 14885     See in Manteia.
MGI - MGI:1338799
RefSeq - XM_006523669
RefSeq - NM_010364
RefSeq - XM_006523668
RefSeq Peptide - NP_034494
swissprot - E0CYM3
swissprot - E0CYK8
swissprot - Q542U3
swissprot - E0CY64
swissprot - E0CXV5
swissprot - O70422
Ensembl - ENSMUSG00000001524
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gtf2h4ENSDARG00000036071Danio rerio
 GTF2H4ENSG00000213780Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR004598  Transcription factor TFIIH subunit p52/Tfb2


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006289 nucleotide-excision repair IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II ISS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0032508 DNA duplex unwinding IEA
 biological_processGO:0070816 phosphorylation of RNA polymerase II C-terminal domain IBA
 cellular_componentGO:0000438 core TFIIH complex portion of holo TFIIH complex ISO
 cellular_componentGO:0000439 core TFIIH complex IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005669 transcription factor TFIID complex ISO
 cellular_componentGO:0005675 holo TFIIH complex IBA
 cellular_componentGO:0016607 nuclear speck ISO
 molecular_functionGO:0003690 double-stranded DNA binding IBA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IBA
 molecular_functionGO:0004003 ATP-dependent DNA helicase activity IEA
 molecular_functionGO:0004672 protein kinase activity ISS
 molecular_functionGO:0008094 DNA-dependent ATPase activity ISS
 molecular_functionGO:0008353 RNA polymerase II carboxy-terminal domain kinase activity IBA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
mRNA Capping
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Pol II CTD phosphorylation and interaction with CE


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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