ENSMUSG00000001627


Mus musculus

Features
Gene ID: ENSMUSG00000001627
  
Biological name :Ifrd1
  
Synonyms : Ifrd1 / Interferon-related developmental regulator 1 / P19182
  
Possible biological names infered from orthology : O00458
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: B1
Gene start: 40201567
Gene end: 40248504
  
Corresponding Affymetrix probe sets: 10400095 (MoGene1.0st)   1416067_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000127553
Ensembl peptide - ENSMUSP00000133028
Ensembl peptide - ENSMUSP00000130846
Ensembl peptide - ENSMUSP00000130824
Ensembl peptide - ENSMUSP00000128635
Ensembl peptide - ENSMUSP00000127673
Ensembl peptide - ENSMUSP00000001672
NCBI entrez gene - 15982     See in Manteia.
MGI - MGI:1316717
RefSeq - NM_013562
RefSeq Peptide - NP_038590
swissprot - E9Q1E6
swissprot - E9PVS0
swissprot - F6TBT6
swissprot - E9QA50
swissprot - P19182
swissprot - E9QA38
swissprot - E9Q949
Ensembl - ENSMUSG00000001627
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ifrd1ENSDARG00000068708Danio rerio
 IFRD1ENSGALG00000009448Gallus gallus
 IFRD1ENSG00000006652Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ifrd2 / interferon related developmental regulator 2 / Q12894*ENSMUSG0000001004850


Protein motifs (from Interpro)
Interpro ID Name
 IPR006921  Interferon-related developmental regulator, C-terminal
 IPR007701  Interferon-related developmental regulator, N-terminal
 IPR011989  Armadillo-like helical
 IPR016024  Armadillo-type fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0014706 striated muscle tissue development IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030517 negative regulation of axon extension IGI
 biological_processGO:0042692 muscle cell differentiation IMP
 biological_processGO:0043403 skeletal muscle tissue regeneration IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0048671 negative regulation of collateral sprouting IGI
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity ISO
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IDA
 molecular_functionGO:0005488 binding IEA
 molecular_functionGO:0061629 RNA polymerase II sequence-specific DNA-binding transcription factor binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000750 abnormal muscle regeneration "inability or defects in ability to repair muscle after injuries" [J:42574]
Show

Allelic Composition: Ptpn22tm2Achn/Ptpn22tm2Achn
Genetic Background: involves: C57BL/6

 MP:0000759 abnormal skeletal muscle morphology "anomalous structure of any of the striated muscle fibers connected at either or both extremeties with the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptpn22tm2Achn/Ptpn22tm2Achn
Genetic Background: involves: C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Ptpn22tm2Achn/Ptpn22tm2Achn
Genetic Background: involves: C57BL/6

 MP:0009426 decreased soleus weight "reduction in the weight of the superficial flat broad muscle of the calf that is responsible for plantar flexion of the foot" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Ptpn22tm2Achn/Ptpn22tm2Achn
Genetic Background: involves: C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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