ENSMUSG00000001663


Mus musculus

Features
Gene ID: ENSMUSG00000001663
  
Biological name :Gstt1
  
Synonyms : Glutathione S-transferase theta-1 / Gstt1 / Q64471
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C1
Gene start: 75783813
Gene end: 75798584
  
Corresponding Affymetrix probe sets: 10370000 (MoGene1.0st)   1418186_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000001713
Ensembl peptide - ENSMUSP00000117130
Ensembl peptide - ENSMUSP00000113839
NCBI entrez gene - 14871     See in Manteia.
MGI - MGI:107379
RefSeq - NM_008185
RefSeq - XM_006513239
RefSeq Peptide - NP_032211
swissprot - D3Z5W7
swissprot - Q64471
swissprot - D3Z3X5
Ensembl - ENSMUSG00000001663
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 gstt1aENSDARG00000042428Danio rerio
 gstt1bENSDARG00000017388Danio rerio
 ENSGALG00000005204Gallus gallus
 GSTT1ENSGALG00000006344Gallus gallus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Gstt3 / Q99L20 / Mus musculus glutathione S-transferase, theta 3 (Gstt3), transcript variant 2, mRNA.ENSMUSG0000000166568
Gm20441ENSMUSG0000009236056
Gstt4 / Q9D4P7 / Glutathione S-transferase theta-4 ENSMUSG0000000909350
Gstt2 / Q61133 / Glutathione S-transferase theta-2 / GSTT2B* / P0CG30* / glutathione S-transferase theta 2 (gene/pseudogene)* / glutathione S-transferase theta 2B (gene/pseudogene)*ENSMUSG0000003331849


Protein motifs (from Interpro)
Interpro ID Name
 IPR004045  Glutathione S-transferase, N-terminal
 IPR004046  Glutathione S-transferase, C-terminal
 IPR010987  Glutathione S-transferase, C-terminal-like
 IPR036249  Thioredoxin-like superfamily
 IPR036282  Glutathione S-transferase, C-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006304 DNA modification IEA
 biological_processGO:0006749 glutathione metabolic process IEA
 biological_processGO:0009751 response to salicylic acid IEA
 biological_processGO:0010269 response to selenium ion IEA
 biological_processGO:0014070 response to organic cyclic compound IEA
 biological_processGO:0018900 dichloromethane metabolic process IEA
 biological_processGO:0033197 response to vitamin E IEA
 biological_processGO:0042493 response to drug IEA
 biological_processGO:0098869 cellular oxidant detoxification IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0004364 glutathione transferase activity IEA
 molecular_functionGO:0004602 glutathione peroxidase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0047651 alkylhalidase activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005559 increased circulating glucose level "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
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Allelic Composition: Gsk3atm1a(EUCOMM)Hmgu/Gsk3atm1a(EUCOMM)Hmgu
Genetic Background: Not Specified

 MP:0008875 abnormal pharmacokinetics of xenobiotics "any anomaly in the absorbtion, distribution, metabolism or elimination of a foreign compound" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Dock1tm1Jfco/Dock1+,Dock5Gt(AN0268)Wtsi/Dock5Gt(AN0268)Wtsi
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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