| MP:0000420 | ruffled hair | "fuzzy, irregular appearance of the hair" [J:50844] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0000876 | Purkinje cell degeneration | "a retrogressive impairment of function or destruction of the large neurons located at the interface of the molecular and internal granule layers of the cerebellar cortex" [J:46854] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0001059 | optic nerve atrophy | "wasting of the second cranial nerve which is responsible for conveying visual information from the retina to the brain" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0001405 | impaired coordination | "reduced ability to execute integrated movements of muscle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0001406 | abnormal gait | "unusual or distinctive way of walking" [J:65038] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0001625 | cardiac hypertrophy | "an increase in size of the cardiac tissue, not due to increased cell number " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0002090 | abnormal vision | "inability or decreased ability to see " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0002953 | thick ventricular wall | "increased depth of the cardiac wall of the heart ventricles" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0003786 | premature aging | "earlier than normal occurence of the normal signs of aging" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:97764] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0008511 | thin retinal inner nuclear layer | "reduced thickness of the retinal layer which contains the cell bodies of bipolar, horizontal, and amacrine cells" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0008519 | thin retinal outer plexiform layer | "reduced thickness of the retinal layer that is the site of synapses between the rods and cones (axons) and the horizontal and bipolar cells (dendrites)" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0010724 | thick interventricular septum | "increased thickness of the wall between the two lower chambers of the heart" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0010955 | abnormal respiratory electron transport chain | "anomaly in the process in which a series of electron carriers operate together to transfer electrons from donors such as NADH and FADH2 to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient" [GO:0022904] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0012017 | grizzled coat color | "amount and distribution of yellow pigment (phaeomelanin) relative to black or brown pigment (eumelanin) is decreased compared to wild-type agouti producing hair that is partly gray or streaked with gray" [MGI:llw2] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0012065 | increased astrocyte number | "increase in the number of the large neuroglial (macroglial) cells in the central nervous system - the largest and most numerous neuroglial cells in the brain and spinal cord" [CL:0000127, MGI:csmith] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
| MP:0020434 | increased astrocyte size | "increase in the size of the large neuroglial (macroglial) cells in the central nervous system" [CL:0000127, MGI:smb] |
Show
Allelic Composition: Col4a1tm1.1Ics/Col4a1+
Genetic Background: involves: 129S2/SvPas * C57BL/6
|
