ENSMUSG00000002265


Mus musculus

Features
Gene ID: ENSMUSG00000002265
  
Biological name :Peg3
  
Synonyms : Paternally-expressed 3 protein / Peg3 / Q3URU2
  
Possible biological names infered from orthology : paternally expressed 3 / Q9GZU2
  
Species: Mus musculus
  
Chr. number: 7
Strand: -1
Band: A1
Gene start: 6703892
Gene end: 6730431
  
Corresponding Affymetrix probe sets: 10559796 (MoGene1.0st)   1417355_at (Mouse Genome 430 2.0 Array)   1417356_at (Mouse Genome 430 2.0 Array)   1433924_at (Mouse Genome 430 2.0 Array)   1447731_at (Mouse Genome 430 2.0 Array)   1447732_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000050750
Ensembl peptide - ENSMUSP00000116161
Ensembl peptide - ENSMUSP00000122423
NCBI entrez gene - 18616     See in Manteia.
MGI - MGI:104748
RefSeq - XM_017322034
RefSeq - NM_008817
RefSeq - XM_017322031
RefSeq - XM_017322032
RefSeq - XM_017322033
RefSeq - XM_017322029
RefSeq - XM_017322030
RefSeq Peptide - NP_032843
swissprot - Q3URU2
swissprot - D6RGA4
Ensembl - ENSMUSG00000002265
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch73-138e16.3ENSDARG00000095745Danio rerio
 si:dkey-3p4.8ENSDARG00000114124Danio rerio
 znf1081ENSDARG00000104561Danio rerio
 znf1082ENSDARG00000104006Danio rerio
 PEG3ENSG00000198300Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Zfp623 / zinc finger protein 623 / O75123* / ZNF623*ENSMUSG0000005084610


Protein motifs (from Interpro)
Interpro ID Name
 IPR013087  Zinc finger C2H2-type
 IPR036236  Zinc finger C2H2 superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IMP
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IGI
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005776 autophagosome IDA
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000837 abnormal hypothalamus morphology "any malformation or absence of the ventral part of the diencephalon extending from the region of the optic chiasm to the caudal border of the mammillary bodies and forming the inferior and lateral walls of the third ventricle; this region regulates the autonomic nervous system via hormone production and release" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Pafah1b1tm1Awb/Pafah1b1+
Genetic Background: involves: 129S6/SvEvTac

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: Peg3tm1a(EUCOMM)Hmgu/Peg3+
Genetic Background: involves: C57BL/6N

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Peg3tm1.1Jkim/Peg3+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Pafah1b1tm1Awb/Pafah1b1+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Peg3tm1.1Jkim/Peg3+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J

Allelic Composition: Peg3tm1a(EUCOMM)Hmgu/Peg3+
Genetic Background: involves: C57BL/6N

 MP:0001384 abnormal pup retrieval "a mother does not retrieve stray pups to the nest or delays retrieving stray pups" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pafah1b1tm1Awb/Pafah1b1+
Genetic Background: involves: 129S6/SvEvTac

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Peg3tm1a(EUCOMM)Hmgu/Peg3+
Genetic Background: involves: C57BL/6N

 MP:0003122 maternal imprinting "specific loci are inactivated during oogenesis and are not expressed in offspring" [llw2:Linda Washburn, Mouse Genome Informatics Curator, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pafah1b1tm1Awb/Pafah1b1+
Genetic Background: involves: 129S6/SvEvTac

 MP:0003787 abnormal imprinting "defect in the normal inactivation of specific loci during gametogenesis" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
Show

Allelic Composition: Peg3tm1.1Jkim/Peg3+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J

 MP:0005431 oocyte depletion "reduced numbers or absence of germ cells in the female" [llw2:Linda Washburn , Mouse Genome Informatics Curator, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Peg3tm1a(EUCOMM)Hmgu/Peg3+
Genetic Background: involves: C57BL/6N

 MP:0009326 abnormal maternal crouching "females do not assume a position over young that facilitates suckling behavior" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pafah1b1tm1Awb/Pafah1b1+
Genetic Background: involves: 129S6/SvEvTac

 MP:0009546 absent gastric milk in neonates "failure of nursing offspring to ingest milk as indicated by stomach content" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Peg3tm1a(EUCOMM)Hmgu/Peg3+
Genetic Background: involves: C57BL/6N

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Peg3tm1a(EUCOMM)Hmgu/Peg3+
Genetic Background: involves: C57BL/6N

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Peg3tm1.1Jkim/Peg3+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6 * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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