ENSMUSG00000002486


Mus musculus

Features
Gene ID: ENSMUSG00000002486
  
Biological name :Tchp
  
Synonyms : Q3TVW5 / Tchp / Trichoplein keratin filament-binding protein
  
Possible biological names infered from orthology : Q9BT92 / trichoplein keratin filament binding
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: F
Gene start: 114707760
Gene end: 114722327
  
Corresponding Affymetrix probe sets: 10524572 (MoGene1.0st)   1438293_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000092009
Ensembl peptide - ENSMUSP00000119890
NCBI entrez gene - 77832     See in Manteia.
MGI - MGI:1925082
RefSeq - XM_006530511
RefSeq - NM_029992
RefSeq - XM_006530508
RefSeq Peptide - NP_084268
swissprot - Q3TVW5
swissprot - F6Q720
Ensembl - ENSMUSG00000002486
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tchpENSDARG00000035605Danio rerio
 TCHPENSGALG00000035049Gallus gallus
 TCHPENSG00000139437Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR001289  Nuclear transcription factor Y subunit A
 IPR026773  Trichoplein keratin filament-binding protein


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006915 apoptotic process ISO
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0030308 negative regulation of cell growth IEA
 biological_processGO:1902018 negative regulation of cilium assembly IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005813 centrosome IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030057 desmosome IDA
 cellular_componentGO:0045095 keratin filament IEA
 cellular_componentGO:0045179 apical cortex IEA
 cellular_componentGO:0097539 ciliary transition fiber IDA
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001556 increased circulating HDL cholesterol level "higher than average level of high density lipoprotein in the blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47439]
Show

Allelic Composition: Sufutm1b(KOMP)Wtsi/Sufutm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd

 MP:0005178 increased total circulating cholesterol level "greater than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Sufutm1b(KOMP)Wtsi/Sufutm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd

 MP:0008174 decreased follicular B cell number "reduced number of resting mature B cells with distinct phenotypic characteristics (CD23-positive, CD21-positive) found typically in the B cell follicle region of the spleen and lymph nodes" [CL:0000843, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Sufutm1b(KOMP)Wtsi/Sufutm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Sufutm1b(KOMP)Wtsi/Ucd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr