ENSMUSG00000003341


Mus musculus

Features
Gene ID: ENSMUSG00000003341
  
Biological name :Atp8b3
  
Synonyms : Atp8b3 / Phospholipid-transporting ATPase IK / Q6UQ17
  
Possible biological names infered from orthology :
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C1
Gene start: 80519584
Gene end: 80539124
  
Corresponding Affymetrix probe sets: 10370860 (MoGene1.0st)   1419713_at (Mouse Genome 430 2.0 Array)   1438604_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000020383
Ensembl peptide - ENSMUSP00000151571
Ensembl peptide - ENSMUSP00000151589
NCBI entrez gene - 67331     See in Manteia.
MGI - MGI:1914581
RefSeq - XM_006513984
RefSeq - NM_026094
RefSeq Peptide - NP_080370
swissprot - Q0VF52
swissprot - Q6UQ17
swissprot - Q9CPY8
Ensembl - ENSMUSG00000003341
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 atp8b1ENSDARG00000060980Danio rerio


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Atp10b / ATPase, class V, type 10B / O94823* / ATPase phospholipid transporting 10B (putative)*ENSMUSG0000005541529
Atp10d / Mus musculus ATPase, class V, type 10D (Atp10d), transcript variant 1, coding, mRNA.ENSMUSG000000468084


Protein motifs (from Interpro)
Interpro ID Name
 IPR001757  P-type ATPase
 IPR006539  P-type ATPase, subfamily IV
 IPR008250  P-type ATPase, A domain superfamily
 IPR018303  P-type ATPase, phosphorylation site
 IPR023214  HAD superfamily
 IPR023298  P-type ATPase, transmembrane domain superfamily
 IPR023299  P-type ATPase, cytoplasmic domain N
 IPR030349  Phospholipid-transporting ATPase IK
 IPR032630  P-type ATPase, C-terminal
 IPR032631  P-type ATPase, N-terminal
 IPR036412  HAD-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006869 lipid transport IEA
 biological_processGO:0007030 Golgi organization IBA
 biological_processGO:0007339 binding of sperm to zona pellucida IMP
 biological_processGO:0015914 phospholipid transport IEA
 biological_processGO:0045332 phospholipid translocation IEA
 cellular_componentGO:0001669 acrosomal vesicle IDA
 cellular_componentGO:0002080 acrosomal membrane IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005789 endoplasmic reticulum membrane IEA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0000287 magnesium ion binding IEA
 molecular_functionGO:0004012 phospholipid-translocating ATPase activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
Show

Allelic Composition: Rpe65tm1Tmr/Rpe65tm1Tmr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rpe65tm1Tmr/Rpe65tm1Tmr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0004542 impaired acrosome reaction "abnormality in the cellular exocytosis that allows sperm to penetrate the zona pellucida of ovulated eggs" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Rpe65tm1Tmr/Rpe65tm1Tmr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005410 abnormal fertilization "anomaly in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rpe65tm1Tmr/Rpe65tm1Tmr
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr