ENSMUSG00000003559


Mus musculus

Features
Gene ID: ENSMUSG00000003559
  
Biological name :As3mt
  
Synonyms : Arsenite methyltransferase / As3mt / Q91WU5
  
Possible biological names infered from orthology : Q9HBK9
  
Species: Mus musculus
  
Chr. number: 19
Strand: 1
Band: C3
Gene start: 46707443
Gene end: 46741095
  
Corresponding Affymetrix probe sets: 10463704 (MoGene1.0st)   1431980_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000003655
NCBI entrez gene - 57344     See in Manteia.
MGI - MGI:1929882
RefSeq - NM_020577
RefSeq - XM_006527235
RefSeq Peptide - NP_065602
swissprot - Q91WU5
Ensembl - ENSMUSG00000003559
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 as3mtENSDARG00000027572Danio rerio
 AS3MTENSGALG00000008133Gallus gallus
 AS3MTENSG00000214435Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR025714  Methyltransferase domain
 IPR029063  S-adenosyl-L-methionine-dependent methyltransferase


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0009404 toxin metabolic process ISS
 biological_processGO:0018872 arsonoacetate metabolic process ISS
 biological_processGO:0032259 methylation IEA
 biological_processGO:0046685 response to arsenic-containing substance ISO
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IDA
 cellular_componentGO:0005829 cytosol ISS
 molecular_functionGO:0008168 methyltransferase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0030791 arsenite methyltransferase activity ISO
 molecular_functionGO:0030792 methylarsonite methyltransferase activity ISS


Pathways (from Reactome)
Pathway description
Methylation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000609 abnormal liver physiology "aberrant function of this bile-secreting exocrine gland, which is important for detoxification; for fat, carbohydrate, and protein metabolism; and for glycogen storage " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Jak2tm1.1Ble/Jak2tm1.1Ble
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0008875 abnormal pharmacokinetics of xenobiotics "any anomaly in the absorbtion, distribution, metabolism or elimination of a foreign compound" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Jak2tm1.1Ble/Jak2tm1.1Ble
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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