ENSMUSG00000004667


Mus musculus

Features
Gene ID: ENSMUSG00000004667
  
Biological name :Polr2e
  
Synonyms : Polr2e / polymerase (RNA) II (DNA directed) polypeptide E / Q80UW8
  
Possible biological names infered from orthology : P19388 / RNA polymerase II subunit E
  
Species: Mus musculus
  
Chr. number: 10
Strand: -1
Band: C1
Gene start: 80035949
Gene end: 80039795
  
Corresponding Affymetrix probe sets: 10370708 (MoGene1.0st)   1417138_s_at (Mouse Genome 430 2.0 Array)   1451093_at (Mouse Genome 430 2.0 Array)   1458326_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000004786
NCBI entrez gene - 66420     See in Manteia.
MGI - MGI:1913670
RefSeq - NM_025554
RefSeq Peptide - NP_079830
swissprot - Q3V214
swissprot - Q80UW8
Ensembl - ENSMUSG00000004667
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 POLR2E (1 of many)ENSDARG00000074274Danio rerio
 polr2ebENSDARG00000026183Danio rerio
 POLR2EENSGALG00000002591Gallus gallus
 P19388ENSG00000099817Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000783  RNA polymerase, subunit H/Rpb5 C-terminal
 IPR005571  RNA polymerase, Rpb5, N-terminal
 IPR014381  DNA-directed RNA polymerase RPB5 subunit, eukaryote/virus
 IPR020608  RNA polymerase, subunit H/Rpb5, conserved site
 IPR020609  Archaeal RpoH /eukaryotic RPB5 RNA polymerase subunit
 IPR035913  RPB5-like RNA polymerase subunit
 IPR036710  RNA polymerase Rpb5, N-terminal domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006360 transcription by RNA polymerase I IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0006383 transcription by RNA polymerase III IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005665 DNA-directed RNA polymerase II, core complex IEA
 cellular_componentGO:0005666 DNA-directed RNA polymerase III complex IBA
 cellular_componentGO:0005736 DNA-directed RNA polymerase I complex IBA
 molecular_functionGO:0001054 RNA polymerase I activity IBA
 molecular_functionGO:0001055 RNA polymerase II activity IBA
 molecular_functionGO:0001056 RNA polymerase III activity IBA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003899 DNA-directed 5"-3" RNA polymerase activity IEA


Pathways (from Reactome)
Pathway description
Formation of RNA Pol II elongation complex
Formation of the Early Elongation Complex
B-WICH complex positively regulates rRNA expression
Transcriptional regulation by small RNAs
RNA Polymerase II Pre-transcription Events
Formation of TC-NER Pre-Incision Complex
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
TP53 Regulates Transcription of DNA Repair Genes
FGFR2 alternative splicing
RNA polymerase II transcribes snRNA genes
mRNA Capping
mRNA Splicing - Major Pathway
mRNA Splicing - Minor Pathway
Processing of Capped Intron-Containing Pre-mRNA
RNA Polymerase I Transcription Initiation
RNA Polymerase I Promoter Escape
RNA Polymerase II Promoter Escape
RNA Polymerase I Chain Elongation
RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
RNA Polymerase I Transcription Termination
RNA Polymerase II Transcription Initiation
RNA Polymerase II Transcription Elongation
RNA Polymerase II Transcription Initiation And Promoter Clearance
RNA Polymerase III Transcription Initiation From Type 1 Promoter
RNA Polymerase III Transcription Initiation From Type 2 Promoter
RNA Polymerase III Transcription Initiation From Type 3 Promoter
RNA Pol II CTD phosphorylation and interaction with CE
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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