ENSMUSG00000004788


Mus musculus

Features
Gene ID: ENSMUSG00000004788
  
Biological name :Eif2b2
  
Synonyms : Eif2b2 / Q99LD9 / Translation initiation factor eIF-2B subunit beta
  
Possible biological names infered from orthology : eukaryotic translation initiation factor 2B subunit beta / P49770
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: D1
Gene start: 85219481
Gene end: 85226628
  
Corresponding Affymetrix probe sets: 10397332 (MoGene1.0st)   1434538_x_at (Mouse Genome 430 2.0 Array)   1437428_x_at (Mouse Genome 430 2.0 Array)   1451136_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000004910
Ensembl peptide - ENSMUSP00000122954
Ensembl peptide - ENSMUSP00000122720
NCBI entrez gene - 217715     See in Manteia.
MGI - MGI:2145118
RefSeq - NM_145445
RefSeq Peptide - NP_663420
swissprot - D3Z7J6
swissprot - D3Z487
swissprot - Q99LD9
Ensembl - ENSMUSG00000004788
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 eif2b2ENSDARG00000041397Danio rerio
 EIF2B2ENSGALG00000010301Gallus gallus
 EIF2B2ENSG00000119718Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000649  Initiation factor 2B-related
 IPR037171  NagB/RpiA transferase-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001541 ovarian follicle development IEA
 biological_processGO:0006412 translation IEA
 biological_processGO:0006413 translational initiation ISO
 biological_processGO:0007417 central nervous system development IEA
 biological_processGO:0014003 oligodendrocyte development IEA
 biological_processGO:0042552 myelination IEA
 biological_processGO:0044237 cellular metabolic process IEA
 biological_processGO:0050852 T cell receptor signaling pathway IEA
 biological_processGO:0065009 regulation of molecular function IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005851 eukaryotic translation initiation factor 2B complex IEA
 molecular_functionGO:0003743 translation initiation factor activity ISO
 molecular_functionGO:0005085 guanyl-nucleotide exchange factor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0005525 GTP binding IEA


Pathways (from Reactome)
Pathway description
Recycling of eIF2:GDP


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005561 increased mean corpuscular hemoglobin "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ehd1tm1a(EUCOMM)Wtsi/Ehd1tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Ehd1tm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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