ENSMUSG00000005732


Mus musculus

Features
Gene ID: ENSMUSG00000005732
  
Biological name :Ranbp1
  
Synonyms : P34022 / Ranbp1 / Ran-specific GTPase-activating protein
  
Possible biological names infered from orthology : P43487 / RAN binding protein 1
  
Species: Mus musculus
  
Chr. number: 16
Strand: -1
Band: A3
Gene start: 18239784
Gene end: 18248732
  
Corresponding Affymetrix probe sets: 10438308 (MoGene1.0st)   1422547_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000055288
Ensembl peptide - ENSMUSP00000111309
NCBI entrez gene - 19385     See in Manteia.
MGI - MGI:96269
RefSeq - NM_011239
RefSeq Peptide - NP_035369
swissprot - H7BX22
swissprot - P34022
Ensembl - ENSMUSG00000005732
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ranbp1ENSDARG00000014817Danio rerio
 RANBP1ENSGALG00000002107Gallus gallus
 P43487ENSG00000099901Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR000156  Ran binding domain
 IPR011993  PH-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000082 G1/S transition of mitotic cell cycle IBA
 biological_processGO:0006405 RNA export from nucleus IBA
 biological_processGO:0006511 ubiquitin-dependent protein catabolic process IBA
 biological_processGO:0006606 protein import into nucleus IBA
 biological_processGO:0007051 spindle organization IDA
 biological_processGO:0010976 positive regulation of neuron projection development IEA
 biological_processGO:0035690 cellular response to drug IEA
 biological_processGO:0043547 positive regulation of GTPase activity IEA
 biological_processGO:0046604 positive regulation of mitotic centrosome separation IDA
 biological_processGO:0046907 intracellular transport IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0051592 response to calcium ion IEA
 biological_processGO:0072750 cellular response to leptomycin B IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005813 centrosome IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0032838 plasma membrane bounded cell projection cytoplasm IEA
 cellular_componentGO:1904115 axon cytoplasm IEA
 molecular_functionGO:0005092 GDP-dissociation inhibitor activity ISO
 molecular_functionGO:0005096 GTPase activator activity IBA
 molecular_functionGO:0008536 Ran GTPase binding IBA
 molecular_functionGO:0045296 cadherin binding ISO


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Slc6a4tm1.1Rbl/Slc6a4tm1.1Rbl
Genetic Background: 129S6/SvEvTac-Slc6a4tm1.1Rbl

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Slc6a4tm1.1Rbl/Slc6a4tm1.1Rbl
Genetic Background: 129S6/SvEvTac-Slc6a4tm1.1Rbl

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Slc6a4tm1.1Rbl/Slc6a4tm1.1Rbl
Genetic Background: 129S6/SvEvTac-Slc6a4tm1.1Rbl

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Slc6a4tm1.1Rbl/Slc6a4tm1.1Rbl
Genetic Background: 129S6/SvEvTac-Slc6a4tm1.1Rbl

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Slc6a4tm1.1Rbl/Slc6a4tm1.1Rbl
Genetic Background: 129S6/SvEvTac-Slc6a4tm1.1Rbl

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Slc6a4tm1.1Rbl/Slc6a4tm1.1Rbl
Genetic Background: 129S6/SvEvTac-Slc6a4tm1.1Rbl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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