ENSMUSG00000007036


Mus musculus

Features
Gene ID: ENSMUSG00000007036
  
Biological name :Abhd16a
  
Synonyms : Abhd16a / abhydrolase domain containing 16A / Q9Z1Q2
  
Possible biological names infered from orthology : O95870
  
Species: Mus musculus
  
Chr. number: 17
Strand: 1
Band: B1
Gene start: 35089263
Gene end: 35102987
  
Corresponding Affymetrix probe sets: 10444685 (MoGene1.0st)   10338332 (MoGene1.0st)   10338817 (MoGene1.0st)   10339148 (MoGene1.0st)   10339306 (MoGene1.0st)   10339945 (MoGene1.0st)   10340112 (MoGene1.0st)   10340242 (MoGene1.0st)   10340643 (MoGene1.0st)   10340951 (MoGene1.0st)   10340978 (MoGene1.0st)   10341194 (MoGene1.0st)   10341338 (MoGene1.0st)   10341986 (MoGene1.0st)   10342154 (MoGene1.0st)   10342290 (MoGene1.0st)   10342298 (MoGene1.0st)   10342406 (MoGene1.0st)   10342562 (MoGene1.0st)   10342746 (MoGene1.0st)   10342783 (MoGene1.0st)   10342829 (MoGene1.0st)   10342920 (MoGene1.0st)   10343530 (MoGene1.0st)   10343670 (MoGene1.0st)   10343770 (MoGene1.0st)   10339534 (MoGene1.0st)   10341839 (MoGene1.0st)   10342273 (MoGene1.0st)   10342437 (MoGene1.0st)   10343321 (MoGene1.0st)   10343323 (MoGene1.0st)   10343395 (MoGene1.0st)   10343931 (MoGene1.0st)   10344527 (MoGene1.0st)   1415732_at (Mouse Genome 430 2.0 Array)   1460709_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000007251
Ensembl peptide - ENSMUSP00000133505
NCBI entrez gene - 193742     See in Manteia.
MGI - MGI:99476
RefSeq - XM_017317352
RefSeq - NM_178592
RefSeq - XM_017317351
RefSeq Peptide - NP_848707
swissprot - Q9Z1Q2
swissprot - G3UX11
Ensembl - ENSMUSG00000007036
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 abhd16aENSDARG00000078929Danio rerio
 O95870ENSG00000204427Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q80YU0 / Abhd16b / abhydrolase domain containing 16B / Q9H3Z7*ENSMUSG0000005588245


Protein motifs (from Interpro)
Interpro ID Name
 IPR000073  Alpha/beta hydrolase fold-1
 IPR026604  Abhydrolase domain-containing protein 16A
 IPR029058  Alpha/Beta hydrolase fold


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0052651 monoacylglycerol catabolic process IDA
 biological_processGO:1905344 prostaglandin catabolic process IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 molecular_functionGO:0016787 hydrolase activity IEA
 molecular_functionGO:0047372 acylglycerol lipase activity IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Smcr8tm1.1(KOMP)Vlcg/Smcr8tm1.1(KOMP)Vlcg
Genetic Background: involves: 129S1/SvImJ * C57BL/6J * C57BL/6NTac

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Smcr8tm1.1(KOMP)Vlcg/Smcr8tm1.1(KOMP)Vlcg
Genetic Background: involves: 129S1/SvImJ * C57BL/6J * C57BL/6NTac

 MP:0002451 abnormal macrophage physiology "abnormal function or response of the phagocytic leukocytes involved in innate immunity, early non-adaptive phases of host-defense, antigen presentation, and which act as effector cells in humoral and cell-mediated immunity" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Smcr8tm1.1(KOMP)Vlcg/Smcr8tm1.1(KOMP)Vlcg
Genetic Background: involves: 129S1/SvImJ * C57BL/6J * C57BL/6NTac

 MP:0004777 abnormal phospholipid level "anomalous concentration of the fat derivatives in which one fatty acid has been replaced by a phosphate group" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Smcr8tm1.1(KOMP)Vlcg/Smcr8tm1.1(KOMP)Vlcg
Genetic Background: involves: 129S1/SvImJ * C57BL/6J * C57BL/6NTac

 MP:0005584 abnormal enzyme/coenzyme activity "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Smcr8tm1.1(KOMP)Vlcg/Smcr8tm1.1(KOMP)Vlcg
Genetic Background: involves: 129S1/SvImJ * C57BL/6J * C57BL/6NTac

 MP:0008561 decreased tumor necrosis factor secretion "reduction in the production or release of a serum glycoprotein produced by activated macrophages and NK cells and involved in initiating local inflammatory responses, particularly by its action on the endothelium of local blood vessels; its actions result in increased vascular permeability and induction of expression of adhesion molecules on the endothelium" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MESH:D12.644.276.374.500.800]
Show

Allelic Composition: Smcr8tm1.1(KOMP)Vlcg/Smcr8tm1.1(KOMP)Vlcg
Genetic Background: involves: 129S1/SvImJ * C57BL/6J * C57BL/6NTac

 MP:0008658 decreased interleukin-1 beta secretion "reduction in the production or release of an interleukin-1 subtype that is synthesized as an inactive membrane-bound pro-protein on monocytes, macrophages and other cells; proteolytic processing of the precursor form by caspase 1 results in release of the active form of interleukin-1beta from the membrane" [MESH:D12.644.276.374.465.501.600]
Show

Allelic Composition: Smcr8tm1.1(KOMP)Vlcg/Smcr8tm1.1(KOMP)Vlcg
Genetic Background: involves: 129S1/SvImJ * C57BL/6J * C57BL/6NTac

 MP:0008706 decreased interleukin-6 secretion "reduction in the production or release of a cytokine that stimulates the growth and differentiation of B-cells and is also a growth factor for hybridomas and plasmacytomas, and is produced by many different cells including T-cells, monocytes and fibroblasts" [MESH:D12.644.276.374.465.506]
Show

Allelic Composition: Smcr8tm1.1(KOMP)Vlcg/Smcr8tm1.1(KOMP)Vlcg
Genetic Background: involves: 129S1/SvImJ * C57BL/6J * C57BL/6NTac

 MP:0011079 decreased macrophage cytokine production "reduced production of macrophage-derived cytokine(s) due to biosynthesis or secretion following a cellular stimulus, resulting in an increase in its intracellular or extracellular levels" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Smcr8tm1.1(KOMP)Vlcg/Smcr8tm1.1(KOMP)Vlcg
Genetic Background: involves: 129S1/SvImJ * C57BL/6J * C57BL/6NTac

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Smcr8tm1.1(KOMP)Vlcg/Smcr8tm1.1(KOMP)Vlcg
Genetic Background: involves: 129S1/SvImJ * C57BL/6J * C57BL/6NTac

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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