Manteia

ENSMUSG00000008140

Mus musculus

Features

Gene ID:	ENSMUSG00000008140

Biological name :	Emc10

Synonyms :	Emc10 / ER membrane protein complex subunit 10 isoform 2

Possible biological names infered from orthology :	ER membrane protein complex subunit 10 / Q5UCC4

Species:	Mus musculus

Chr. number:	7
Strand:	-1
Band:	B3
Gene start:	44489937
Gene end:	44496529

Corresponding Affymetrix probe sets:	10562774 (MoGene1.0st) 1424038_a_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000113141 Ensembl peptide - ENSMUSP00000116293 Ensembl peptide - ENSMUSP00000113509 NCBI entrez gene - 69683 See in Manteia. MGI - MGI:1916933 RefSeq - XM_006541176 RefSeq - NM_197991 RefSeq - XM_006541175 RefSeq Peptide - NP_001342036 RefSeq Peptide - NP_932108 swissprot - D3Z665 swissprot - A0A0X1KG66 swissprot - A0A0X1KG67 Ensembl - ENSMUSG00000008140

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
emc10	ENSDARG00000054793	Danio rerio
EMC10	ENSG00000161671	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name

Similarity(%)

No match

Protein motifs (from Interpro)

Interpro ID	Name
IPR029615	ER membrane protein complex subunit 10

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0072546	ER membrane protein complex	IEA

Pathways (from Reactome)

Pathway description

No match

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000280	thin ventricular wall	"decreased depth of the cardiac wall of the heart ventricles" [J:45302]	Show Allelic Composition: Elmod1^{tm1b(EUCOMM)Hmgu}/Elmod1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Elmod1^{tm1b(EUCOMM)Hmgu}/H
MP:0001289	persistence of hyaloid capillary system	"failure of the degeneration of the transient vascular system of the eye during development" [J:49840]	Show Allelic Composition: Elmod1^{tm1b(EUCOMM)Hmgu}/Elmod1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Elmod1^{tm1b(EUCOMM)Hmgu}/H
MP:0001363	increased anxiety-related response	"when compared to controls, subjects exhibit more responses thought to be indicative of anxiety in behavioral tests" [cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:49752, J:53060]	Show Allelic Composition: Pin1^tm1Tuc/Pin1^tm1Tuc,Tg(APPSWE)2576Kha/0 Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * SJL
MP:0001399	hyperactivity	"general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]	Show Allelic Composition: Elmod1^{tm1b(EUCOMM)Hmgu}/Elmod1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Elmod1^{tm1b(EUCOMM)Hmgu}/H
MP:0001406	abnormal gait	"unusual or distinctive way of walking" [J:65038]	Show Allelic Composition: Elmod1^{tm1b(EUCOMM)Hmgu}/Elmod1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Elmod1^{tm1b(EUCOMM)Hmgu}/H
MP:0001529	abnormal vocalization	"an inability, decreased ability or altered ability to produce sound from the vocal organs; or a general increase or decrease in the production of vocal sound" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:85479]	Show Allelic Composition: Elmod1^{tm1b(EUCOMM)Hmgu}/Elmod1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Elmod1^{tm1b(EUCOMM)Hmgu}/H
MP:0001922	reduced male fertility	"reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]	Show Allelic Composition: Pin1^tm1Tuc/Pin1^tm1Tuc,Tg(APPSWE)2576Kha/0 Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * SJL
MP:0002591	decreased mean corpuscular volume	"less than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Elmod1^{tm1b(EUCOMM)Hmgu}/Elmod1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Elmod1^{tm1b(EUCOMM)Hmgu}/H
MP:0002834	decreased heart weight	"less than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]	Show Allelic Composition: Elmod1^{tm1b(EUCOMM)Hmgu}/Elmod1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Elmod1^{tm1b(EUCOMM)Hmgu}/H
MP:0003179	decreased platelet count	"fewer than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, hdene:Howard Dene , Mouse Genome Informatics Curator, J:93052]	Show Allelic Composition: Elmod1^{tm1b(EUCOMM)Hmgu}/Elmod1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Elmod1^{tm1b(EUCOMM)Hmgu}/H
MP:0005292	improved glucose tolerance	"better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pin1^tm1Tuc/Pin1^tm1Tuc,Tg(APPSWE)2576Kha/0 Genetic Background: involves: 129 * 129P2/OlaHsd * C57BL/6 * SJL
MP:0005419	hypoalbuminemia	"blood albumin concentration below the normal range" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Elmod1^{tm1b(EUCOMM)Hmgu}/Elmod1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Elmod1^{tm1b(EUCOMM)Hmgu}/H
MP:0005560	decreased circulating glucose level	"less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Elmod1^{tm1b(EUCOMM)Hmgu}/Elmod1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Elmod1^{tm1b(EUCOMM)Hmgu}/H
MP:0010124	decreased bone mineral content	"reduction in the amount (usually in grams/cm) of bone mineral divided by a bone-scanned area" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Elmod1^{tm1b(EUCOMM)Hmgu}/Elmod1^{tm1b(EUCOMM)Hmgu} Genetic Background: C57BL/6N-Elmod1^{tm1b(EUCOMM)Hmgu}/H

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

0 s.

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		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr