ENSMUSG00000009035


Mus musculus

Features
Gene ID: ENSMUSG00000009035
  
Biological name :Tmem184b
  
Synonyms : Q8BG09 / Tmem184b / Transmembrane protein 184B
  
Possible biological names infered from orthology : Q9Y519
  
Species: Mus musculus
  
Chr. number: 15
Strand: -1
Band: E1
Gene start: 79360684
Gene end: 79403569
  
Corresponding Affymetrix probe sets: 10430510 (MoGene1.0st)   1427059_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000155585
Ensembl peptide - ENSMUSP00000136416
Ensembl peptide - ENSMUSP00000154053
Ensembl peptide - ENSMUSP00000154210
Ensembl peptide - ENSMUSP00000074518
Ensembl peptide - ENSMUSP00000155214
NCBI entrez gene - 223693     See in Manteia.
MGI - MGI:2445179
RefSeq - XM_011245585
RefSeq - NM_001253817
RefSeq - NM_001253819
RefSeq - NM_001253820
RefSeq - NM_172608
RefSeq - XM_006520804
RefSeq - XM_006520805
RefSeq - XM_006520806
RefSeq - XM_006520807
RefSeq Peptide - NP_001240746
RefSeq Peptide - NP_001240748
RefSeq Peptide - NP_001240749
RefSeq Peptide - NP_766196
swissprot - Q8BG09
Ensembl - ENSMUSG00000009035
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:dkey-217f16.5ENSDARG00000090876Danio rerio
 tmem184baENSDARG00000045147Danio rerio
 tmem184bbENSDARG00000091956Danio rerio
 TMEM184BENSGALG00000012272Gallus gallus
 Q9Y519ENSG00000198792Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Q3UFJ6 / Tmem184a / transmembrane protein 184a / Q6ZMB5*ENSMUSG0000003668761
Q3TPR7 / Tmem184c / Transmembrane protein 184C / Q9NVA4*ENSMUSG0000003161728
Gm26938 / Q6ZMB5* / TMEM184A* / transmembrane protein 184A*ENSMUSG0000009814018


Protein motifs (from Interpro)
Interpro ID Name
 IPR005178  Organic solute transporter subunit alpha/Transmembrane protein 184


Gene Ontology (GO)
TypeGO IDTermEv.Code
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IBA
 molecular_functionGO:0005215 transporter activity IBA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000266 abnormal cardiac morphology "anomalies in the hollow, muscular organ that maintains the circulation of the blood" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Syt1tm1a(EUCOMM)Wtsi/Syt1tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Syt1tm1a(EUCOMM)Wtsi/Wtsi

 MP:0000274 enlarged heart "increase over normal size of the heart" [J:29971]
Show

Allelic Composition: Syt1tm1a(EUCOMM)Wtsi/Syt1tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Syt1tm1a(EUCOMM)Wtsi/Wtsi

 MP:0001053 abnormal neuromuscular synapse "malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159, J:47439]
Show

Allelic Composition: Kdm2bGt(RRT043)Byg/Kdm2bGt(RRT043)Byg
Genetic Background: B6.129P2-Kdm2bGt(RRT043)Byg

 MP:0002229 CNS neurodegeneration "a retrogressive impairment of function or destruction of neural tissue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Kdm2bGt(RRT043)Byg/Kdm2bGt(RRT043)Byg
Genetic Background: B6.129P2-Kdm2bGt(RRT043)Byg

 MP:0003084 abnormal skeletal muscle fiber morphology "anomalous structure of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [smb:Susan M. Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Kdm2bGt(RRT043)Byg/Kdm2bGt(RRT043)Byg
Genetic Background: B6.129P2-Kdm2bGt(RRT043)Byg

 MP:0003632 abnormal nervous system morphology 
Show

Allelic Composition: Kdm2bGt(RRT043)Byg/Kdm2bGt(RRT043)Byg
Genetic Background: B6.129P2-Kdm2bGt(RRT043)Byg

 MP:0003633 abnormal nervous system physiology 
Show

Allelic Composition: Kdm2bGt(RRT043)Byg/Kdm2bGt(RRT043)Byg
Genetic Background: B6.129P2-Kdm2bGt(RRT043)Byg

 MP:0005404 abnormal axon morphology "anomaly in the structure of the single process of a nerve cell that normally conducts impulses away from the cell body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Kdm2bGt(RRT043)Byg/Kdm2bGt(RRT043)Byg
Genetic Background: B6.129P2-Kdm2bGt(RRT043)Byg

 MP:0005405 axon degeneration "retrogressive pathologic change in the single process of a nerve cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Kdm2bGt(RRT043)Byg/Kdm2bGt(RRT043)Byg
Genetic Background: B6.129P2-Kdm2bGt(RRT043)Byg

 MP:0008260 abnormal autophagy "abnormal catabolic process involving the degradation of a cell s own components through the lysosomal machinery" [MGI:honda "Hiraoki Onda, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Kdm2bGt(RRT043)Byg/Kdm2bGt(RRT043)Byg
Genetic Background: B6.129P2-Kdm2bGt(RRT043)Byg

 MP:0008571 abnormal synaptic bouton morphology "any structural anomaly of the knoblike enlargements along the course of axons, or more commonly at the distal terminations of axons which are specialized for the release of neurotransmitters" [MESH:A08.663.542.145.750]
Show

Allelic Composition: Kdm2bGt(RRT043)Byg/Kdm2bGt(RRT043)Byg
Genetic Background: B6.129P2-Kdm2bGt(RRT043)Byg

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Kdm2bGt(RRT043)Byg/Kdm2bGt(RRT043)Byg
Genetic Background: B6.129P2-Kdm2bGt(RRT043)Byg

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Syt1tm1a(EUCOMM)Wtsi/Syt1tm1a(EUCOMM)Wtsi
Genetic Background: C57BL/6N-Syt1tm1a(EUCOMM)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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