ENSMUSG00000009207


Mus musculus

Features
Gene ID: ENSMUSG00000009207
  
Biological name :Lnpk
  
Synonyms : Lnpk / lunapark, ER junction formation factor / Q7TQ95
  
Possible biological names infered from orthology : Q9C0E8
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: C3
Gene start: 74520291
Gene end: 74579435
  
Corresponding Affymetrix probe sets: 10483770 (MoGene1.0st)   1429120_at (Mouse Genome 430 2.0 Array)   1453035_at (Mouse Genome 430 2.0 Array)   1456859_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099737
Ensembl peptide - ENSMUSP00000123058
Ensembl peptide - ENSMUSP00000122488
Ensembl peptide - ENSMUSP00000120494
Ensembl peptide - ENSMUSP00000107624
Ensembl peptide - ENSMUSP00000066891
NCBI entrez gene - 69605     See in Manteia.
MGI - MGI:1918115
RefSeq - XM_006500147
RefSeq - NM_001110209
RefSeq - NM_027133
RefSeq - XM_006500145
RefSeq - XM_006500146
RefSeq Peptide - NP_001103679
RefSeq Peptide - NP_081409
swissprot - A2ASL8
swissprot - A2ASM1
swissprot - Q7TQ95
swissprot - A2ASM0
swissprot - A2ASM2
Ensembl - ENSMUSG00000009207
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 lnpaENSDARG00000063646Danio rerio
 lnpaENSDARG00000115902Danio rerio
 lnpkENSDARG00000006639Danio rerio
 LNPKENSGALG00000037944Gallus gallus
 LNPKENSG00000144320Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR019273  Lunapark domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007596 blood coagulation IMP
 biological_processGO:0032330 regulation of chondrocyte differentiation IMP
 biological_processGO:0035115 embryonic forelimb morphogenesis IMP
 biological_processGO:0042733 embryonic digit morphogenesis IGI
 biological_processGO:0071788 endoplasmic reticulum tubular network maintenance IEA
 biological_processGO:1903373 positive regulation of endoplasmic reticulum tubular network organization IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005789 endoplasmic reticulum membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030176 integral component of endoplasmic reticulum membrane IEA
 cellular_componentGO:0098826 endoplasmic reticulum tubular network membrane IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000060 delayed bone ossification "late onset of the formation of bone" [J:40203]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Tbx21tm1Glm/Tbx21tm1Glm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac

Allelic Composition: LnpkUl/LnpkUl
Genetic Background: involves: C3H/HeJ * C57BL/6J * MOLF/Ei

 MP:0000558 abnormal tibia morphology "atructural anomaly of the medial and larger of the two bones of the lower leg" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: LnpkUl/Lnpk+
Genetic Background: involves: 101/H * C3H/HeJ * C57BL/6J

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: LnpkUl/Lnpk+
Genetic Background: involves: 101/H * C3H/HeJ * C57BL/6J

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Tbx21tm1Glm/Tbx21tm1Glm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac

Allelic Composition: LnpkUl/Lnpk+
Genetic Background: involves: C3H/HeJ * C57BL/6J * FVB/N

 MP:0002109 abnormal limb morphology "abnormal development of limbs resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Rag2tm1Fwa/Rag2tm1Fwa,Tbx21tm1Glm/Tbx21tm1Glm
Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac

Allelic Composition: LnpkUl/LnpkUl
Genetic Background: involves: C3H/HeJ * C57BL/6J * MOLF/Ei

 MP:0002187 abnormal fibula morphology "malformation of the lateral and smaller bone of the lower limb" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: LnpkUl/Lnpk+
Genetic Background: involves: 101/H * C3H/HeJ * C57BL/6J

 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: LnpkUl/LnpkUl
Genetic Background: involves: C3H/HeJ * C57BL/6J * FVB/N

Allelic Composition: LnpkUl/LnpkUl
Genetic Background: involves: C3H/HeJ * C57BL/6J * MOLF/Ei

 MP:0002765 short fibula "reduced length of the lateral and smaller of bone of the lower leg" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:12736]
Show

Allelic Composition: LnpkUl/Lnpk+
Genetic Background: involves: 101/H * C3H/HeJ * C57BL/6J

Allelic Composition: LnpkUl/LnpkUl
Genetic Background: involves: C3H/HeJ * C57BL/6J * FVB/N

Allelic Composition: LnpkUl/LnpkUl
Genetic Background: involves: C3H/HeJ * C57BL/6J * MOLF/Ei

 MP:0003072 abnormal metatarsal bone morphology "anomaly in the five bones of the hindpaws that articulate proximally with the cuneiform and cuboid bones of the tarsus and distally with the phlanges" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935]
Show

Allelic Composition: LnpkUl/Lnpk+
Genetic Background: involves: 101/H * C3H/HeJ * C57BL/6J

 MP:0003073 abnormal metacarpal bone morphology "anomaly in the five bones of the forepaws that articulate proximally with the carpal bones and distally with the phlanges" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, Anatomy of the Rat:Greene, EC, Hafner Publishing Co, 1935]
Show

Allelic Composition: LnpkUl/Lnpk+
Genetic Background: involves: 101/H * C3H/HeJ * C57BL/6J

 MP:0004355 short radius "reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: LnpkUl/Lnpk+
Genetic Background: involves: 101/H * C3H/HeJ * C57BL/6J

Allelic Composition: LnpkUl/LnpkUl
Genetic Background: involves: C3H/HeJ * C57BL/6J * FVB/N

Allelic Composition: LnpkUl/LnpkUl
Genetic Background: involves: C3H/HeJ * C57BL/6J * MOLF/Ei

 MP:0004358 bowed tibia "increased curvature of the medial and larger of the two bones of the lower leg" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: LnpkUl/Lnpk+
Genetic Background: involves: 101/H * C3H/HeJ * C57BL/6J

Allelic Composition: LnpkUl/LnpkUl
Genetic Background: involves: C3H/HeJ * C57BL/6J * FVB/N

Allelic Composition: LnpkUl/LnpkUl
Genetic Background: involves: C3H/HeJ * C57BL/6J * MOLF/Ei

 MP:0004359 short ulna "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tektm1Dmt/Tektm1Dmt
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

Allelic Composition: LnpkUl/Lnpk+
Genetic Background: involves: 101/H * C3H/HeJ * C57BL/6J

Allelic Composition: LnpkUl/LnpkUl
Genetic Background: involves: C3H/HeJ * C57BL/6J * FVB/N

Allelic Composition: LnpkUl/LnpkUl
Genetic Background: involves: C3H/HeJ * C57BL/6J * MOLF/Ei

 MP:0005606 increased bleeding time "greater than the normal duration of blood flow after skin puncture; indicative of platelet and capillary function" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission]
Show

Allelic Composition: Papss2bm/Papss2bm
Genetic Background: B6C3Fe a/a-Papss2bm/J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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