ENSMUSG00000009628


Mus musculus

Features
Gene ID: ENSMUSG00000009628
  
Biological name :Tex15
  
Synonyms : F8VPN2 / Testis-expressed protein 15 / Tex15
  
Possible biological names infered from orthology : Q9BXT5 / testis expressed 15, meiosis and synapsis associated
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: A3
Gene start: 33516738
Gene end: 33585582
  
Corresponding Affymetrix probe sets: 10571252 (MoGene1.0st)   1420719_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000138070
Ensembl peptide - ENSMUSP00000009772
Ensembl peptide - ENSMUSP00000114474
Ensembl peptide - ENSMUSP00000120744
NCBI entrez gene - 104271     See in Manteia.
MGI - MGI:1934816
RefSeq - XM_011242106
RefSeq - NM_031374
RefSeq - XM_006508975
RefSeq - XM_006508976
RefSeq - XM_006508977
RefSeq - XM_006508979
RefSeq Peptide - NP_113551
swissprot - F8VPN2
swissprot - M0QWY2
swissprot - E9PY31
swissprot - D3YVF5
Ensembl - ENSMUSG00000009628
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 TEX15ENSG00000133863Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR022188  Protein of unknown function DUF3715
 IPR026616  Testis-expressed sequence 15 protein
 IPR032765  Testis expressed sequence 15 domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus IEA
 biological_processGO:0007129 synapsis IMP
 biological_processGO:0007130 synaptonemal complex assembly IMP
 biological_processGO:0007140 male meiotic nuclear division IMP
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0009566 fertilization IMP
 biological_processGO:0010569 regulation of double-strand break repair via homologous recombination IMP
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030539 male genitalia development IMP
 biological_processGO:0032880 regulation of protein localization IMP
 biological_processGO:0034502 protein localization to chromosome IMP
 biological_processGO:0048873 homeostasis of number of cells within a tissue IMP
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0005575 cellular_component ND
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0003674 molecular_function ND


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Hps5ru2-2Btlr/Hps5ru2-2Btlr
Genetic Background: C57BL/6J-Hps5ru2-2Btlr

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Hps5ru2-2Btlr/Hps5ru2-2Btlr
Genetic Background: C57BL/6J-Hps5ru2-2Btlr

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hps5ru2-2Btlr/Hps5ru2-2Btlr
Genetic Background: C57BL/6J-Hps5ru2-2Btlr

 MP:0004901 decreased male germ cell number "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Hps5ru2-2Btlr/Hps5ru2-2Btlr
Genetic Background: C57BL/6J-Hps5ru2-2Btlr

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Hps5ru2-2Btlr/Hps5ru2-2Btlr
Genetic Background: C57BL/6J-Hps5ru2-2Btlr

 MP:0010948 abnormal double-strand DNA break repair "any annomaly in the process of repair of double-strand breaks in DNA via homologous and nonhomologous mechanisms to reform a continuous DNA helix" [GO:0006302]
Show

Allelic Composition: Hps5ru2-2Btlr/Hps5ru2-2Btlr
Genetic Background: C57BL/6J-Hps5ru2-2Btlr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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