ENSMUSG00000009640


Mus musculus

Features
Gene ID: ENSMUSG00000009640
  
Biological name :Dmap1
  
Synonyms : Dmap1 / DNA methyltransferase 1-associated protein 1 / Q9JI44
  
Possible biological names infered from orthology : Q9NPF5
  
Species: Mus musculus
  
Chr. number: 4
Strand: -1
Band: D2.1
Gene start: 117674681
Gene end: 117682273
  
Corresponding Affymetrix probe sets: 10515481 (MoGene1.0st)   1417742_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099748
NCBI entrez gene - 66233     See in Manteia.
MGI - MGI:1913483
RefSeq - XM_006503268
RefSeq - NM_023178
RefSeq - XM_006503266
RefSeq - XM_006503267
RefSeq Peptide - NP_075667
swissprot - Q9JI44
Ensembl - ENSMUSG00000009640
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 dmap1ENSDARG00000042087Danio rerio
 DMAP1ENSGALG00000010104Gallus gallus
 DMAP1ENSG00000178028Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR008468  DNA methyltransferase 1-associated 1
 IPR027109  SWR1-complex protein 4/DNA methyltransferase 1-associated protein 1
 IPR032563  DAMP1, SANT/Myb-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006281 DNA repair IEA
 biological_processGO:0006325 chromatin organization IEA
 biological_processGO:0006338 chromatin remodeling IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0042993 obsolete positive regulation of transcription factor import into nucleus IEA
 biological_processGO:0043967 histone H4 acetylation IBA
 biological_processGO:0043968 histone H2A acetylation ISO
 biological_processGO:0045471 response to ethanol IEA
 biological_processGO:0045892 negative regulation of transcription, DNA-templated IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005657 replication fork IDA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0035267 NuA4 histone acetyltransferase complex ISO
 molecular_functionGO:0001103 RNA polymerase II repressing transcription factor binding IEA
 molecular_functionGO:0003714 transcription corepressor activity IDA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002727 decreased circulating insulin level "less than normal levels of insulin in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, dlb:Donna Burkart , Mouse Genome Informatics Curator]
Show

Allelic Composition: Asf1atm1b(KOMP)Wtsi/Asf1a+
Genetic Background: C57BL/6N-Asf1atm1b(KOMP)Wtsi/J

 MP:0004179 transmission ratio distortion "the occurence of an allele or haplotype in the offspring of an organism at skewed Mendelian ratios" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Dmap1tm1.2Jrc/Dmap1tm1.2Jrc,Dnmt1tm2Jrc/Dnmt1tm2Jrc
Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL

 MP:0008877 abnormal DNA methylation "any anomaly in the covalent transfer of a methyl group to either N-6 of adenine or C-5 or N-4 of cytosine of DNA" [GO:0006306]
Show

Allelic Composition: Dmap1tm1.2Jrc/Dmap1tm1.2Jrc,Dnmt1tm2Jrc/Dnmt1tm2Jrc
Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL

 MP:0011094 complete embryonic lethality before implantation "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith]
Show

Allelic Composition: Atp7aMo-ml/Y
Genetic Background: involves: C3Hf/He * C57BL/6

Allelic Composition: Dmap1tm1.2Jrc/Dmap1tm1.2Jrc,Dnmt1tm2Jrc/Dnmt1tm2Jrc
Genetic Background: involves: 129S1/Sv * C57BL/6 * FVB/N * SJL

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Wtsi

 MP:0013292 embryonic lethality prior to organogenesis "death prior to the completion of embryo turning (Mus: E9-9.5)" [MGI:smb]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Wtsi

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
Show

Allelic Composition: Dbn1tm1b(KOMP)Wtsi/Dbn1tm1b(KOMP)Wtsi
Genetic Background: C57BL/6N-Dbn1tm1b(KOMP)Wtsi/Wtsi

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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