ENSMUSG00000009670


Mus musculus

Features
Gene ID: ENSMUSG00000009670
  
Biological name :Tex11
  
Synonyms : Q14AT2 / Testis-expressed protein 11 / Tex11
  
Possible biological names infered from orthology : Q8IYF3 / testis expressed 11
  
Species: Mus musculus
  
Chr. number: X
Strand: -1
Band: D
Gene start: 100838648
Gene end: 101059667
  
Corresponding Affymetrix probe sets: 10605954 (MoGene1.0st)   1419729_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000009814
Ensembl peptide - ENSMUSP00000109345
Ensembl peptide - ENSMUSP00000109347
NCBI entrez gene - 83558     See in Manteia.
MGI - MGI:1933237
RefSeq - NM_001167997
RefSeq - NM_031384
RefSeq Peptide - NP_001161469
RefSeq Peptide - NP_113561
swissprot - Q14AT2
Ensembl - ENSMUSG00000009670
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tex11ENSDARG00000078995Danio rerio
 TEX11ENSGALG00000005775Gallus gallus
 TEX11ENSG00000120498Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013940  Meiosis specific protein Spo22/ZIP4/TEX11


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000712 resolution of meiotic recombination intermediates IMP
 biological_processGO:0006311 meiotic gene conversion IMP
 biological_processGO:0007060 male meiosis chromosome segregation IMP
 biological_processGO:0007130 synaptonemal complex assembly IMP
 biological_processGO:0007131 reciprocal meiotic recombination IMP
 biological_processGO:0007140 male meiotic nuclear division IMP
 biological_processGO:0008584 male gonad development IMP
 biological_processGO:0009566 fertilization IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0051026 chiasma assembly IMP
 biological_processGO:0051321 meiotic cell cycle IEA
 cellular_componentGO:0000794 condensed nuclear chromosome IDA
 cellular_componentGO:0000795 synaptonemal complex IDA
 cellular_componentGO:0000801 central element IDA
 cellular_componentGO:0005694 chromosome IEA
 molecular_functionGO:0005515 protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
Show

Allelic Composition: Relatm1Yuo/Relatm1Yuo
Genetic Background: involves: 129S/SvEv

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Tex11tm1Jw/Tex11tm1Jw,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Foxc2tm1Blh/Foxc2+
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0004218 meiotic nondisjunction during M1 phase "abnormal separation of pairs of homologous chromosomes during anaphase of the first meiotic division such that each daughter cell receives one set of paired chromosomes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex11tm1Jw/Tex11tm1Jw,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex11tm1Jw/Tex11tm1Jw,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Relatm1Yuo/Relatm1Yuo
Genetic Background: involves: 129S/SvEv

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Tex11tm1Jw/Tex11tm1Jw,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex11tm1Jw/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

 MP:0008966 abnormal chiasmata formation "atypical contact between nonsister chromatids of homologous chromosomes during meiosis I, precluding formation of the expected number of cross-shaped configurations representing recombination events" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Tex11tm1Jw/Tex11tm1Jw,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

Allelic Composition: Tex11tm1Jw/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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