ENSMUSG00000010045


Mus musculus

Features
Gene ID: ENSMUSG00000010045
  
Biological name :Tmem115
  
Synonyms : Q9WUH1 / Tmem115 / transmembrane protein 115
  
Possible biological names infered from orthology : Q12893
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: F1
Gene start: 107533945
Gene end: 107538673
  
Corresponding Affymetrix probe sets: 10588638 (MoGene1.0st)   1448567_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000010189
NCBI entrez gene - 56395     See in Manteia.
MGI - MGI:1930765
RefSeq - NM_019704
RefSeq Peptide - NP_062678
swissprot - Q543Y8
swissprot - Q9WUH1
Ensembl - ENSMUSG00000010045
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tmem115ENSDARG00000055763Danio rerio
 TMEM115ENSGALG00000026965Gallus gallus
 Q12893ENSG00000126062Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR013861  Transmembrane protein DUF1751, eukaryotic
 IPR035952  Rhomboid-like superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006486 protein glycosylation IEA
 biological_processGO:0006890 retrograde vesicle-mediated transport, Golgi to ER ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005794 Golgi apparatus IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0017119 Golgi transport complex ISS
 cellular_componentGO:0032580 Golgi cisterna membrane ISS
 molecular_functionGO:0003674 molecular_function ND
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
COPI-mediated anterograde transport


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0002192 hydrops fetalis "an abnormal accumulation of serous fluid in fetal tissues" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl

Allelic Composition: Tmem115tm1.1(KOMP)Vlcg/Tmem115+
Genetic Background: C57BL/6N-Tmem115tm1.1(KOMP)Vlcg/Ucd

 MP:0013293 embryonic lethality prior to tooth bud stage "death prior to the appearance of tooth buds (Mus: E12-E12.5)" [MGI:smb]
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Allelic Composition: Enhotm1.1Butl/Enho+
Genetic Background: B6.Cg-Enhotm1.1Butl

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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