ENSMUSG00000010136


Mus musculus

Features
Gene ID: ENSMUSG00000010136
  
Biological name :Pifo
  
Synonyms : Pifo / Protein pitchfork / Q9D9W1
  
Possible biological names infered from orthology : primary cilia formation / Q8TCI5
  
Species: Mus musculus
  
Chr. number: 3
Strand: -1
Band: F2.2
Gene start: 105996957
Gene end: 106014646
  
Corresponding Affymetrix probe sets: 10500999 (MoGene1.0st)   1453320_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000010280
Ensembl peptide - ENSMUSP00000069454
NCBI entrez gene - 100503311     See in Manteia.
MGI - MGI:1923670
RefSeq - NM_001200028
RefSeq - NM_029604
RefSeq Peptide - NP_001186957
RefSeq Peptide - NP_083880
swissprot - Q9D9W1
Ensembl - ENSMUSG00000010136
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:ch211-66i15.4ENSDARG00000097071Danio rerio
 PIFOENSGALG00000023763Gallus gallus
 PIFOENSG00000173947Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR010736  Sperm-tail PG-rich repeat
 IPR033602  Protein pitchfork


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0030030 cell projection organization IEA
 biological_processGO:0031344 regulation of cell projection organization IMP
 biological_processGO:0033674 positive regulation of kinase activity ISS
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005795 Golgi stack IEA
 cellular_componentGO:0005802 trans-Golgi network IDA
 cellular_componentGO:0031410 cytoplasmic vesicle IEA
 cellular_componentGO:0036064 ciliary basal body IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0017137 Rab GTPase binding ISO
 molecular_functionGO:0019894 kinesin binding IPI
 molecular_functionGO:0019901 protein kinase binding IPI
 molecular_functionGO:0043015 gamma-tubulin binding IDA
 molecular_functionGO:0048487 beta-tubulin binding IDA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000284 double outlet right ventricle "both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826]
Show

Allelic Composition: Pkd1tm1Gztn/Pkd1tm1Gztn,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6

 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Pkd1tm1Gztn/Pkd1tm1Gztn,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6

 MP:0001706 abnormal left-right axis patterning "anomaly in the formation or development of the body or a specific organ of the body in relation to the left and right sides of the body or organ" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pkd1tm1Gztn/Pkd1tm1Gztn,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: Pkd1tm1Gztn/Pkd1tm1Gztn,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6

 MP:0004046 abnormal mitosis "anomaly in the process of cell division including both division of the nucleus (karyokinesis) and the cytoplasm (cytokinesis) " [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pkd1tm1Gztn/Pkd1tm1Gztn,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6

 MP:0004066 abnormal Henson s node morphology "malformation of cells in the small pit at the anterior end of the primitive streak that are important in determining left-right asymmetry" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pkd1tm1Gztn/Pkd1tm1Gztn,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6

 MP:0004131 abnormal embryonic ciliary morphology "any structural malformation of the earliest cilia of the mouse embryo found on the cells of the embryonic node" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Pkd1tm1Gztn/Pkd1tm1Gztn,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pkd1tm1Gztn/Pkd1tm1Gztn,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6

 MP:0008933 abnormal embryonic cilium physiology "any functional anomaly of the earliest cilia of the mouse embryo found on the cells of the embryonic node" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Pkd1tm1Gztn/Pkd1tm1Gztn,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Pkd1tm1Gztn/Pkd1tm1Gztn,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: 129S/Sv * 129S7/SvEvBrd * C57BL/6

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr